Results 121 to 130 of about 542,634 (177)

Immunological and pathological roles of Siglecs: a molecular review. [PDF]

Front Immunol
K L, Sundararajan V.
europepmc   +1 more source

CAR T Cells Targeting O-Glycosylated Fibronectin Exhibit Potent Cytolytic Activity and Combine with Tumoral Toll-Like Receptor Agonism to Overcome Tumor Resistance. [PDF]

Cancer Immunol Res
King-Peoples TR, Keane JT, Lewis HS, Liu F, Brookens SK, Dagher OK, Parvathaneni K, Gardner BL, Ahmed A, Furth EE, Lal P, Posey AD.   +11 more
europepmc   +1 more source

Glycosylated extracellular matrix drives immune suppression by modulating macrophage-T cell crosstalk in triple-negative breast cancer. [PDF]

Nat Commun
Tarantola L, Tyler EJ, Liu Y, Maniati E, Thornton KA, Martín-Otal C, Hanna D, Kumar R, Gauthier V, Hirani P, Burger Ramos M, Roth NJ, Bragg J, Puttock EH, McDermott J, Rajeeve V, Cutillas P, Maiques O, Soulier A, Correa de Sampaio P, Jones LJ, Davies DM, Maher J, Haslam SM, Läubli H, Pearce OMT.   +25 more
europepmc   +1 more source

Mass Spectrometry-Based Proteomics Methods for Systematic Identification and Quantification of Protein O-Glycosylation in Complex Biological Samples. [PDF]

J Am Soc Mass Spectrom
Fu L, Xu X, Wu R.
europepmc   +1 more source

Immunomodulation by glycosylation: bridging glycobiology to adaptive immunity and therapeutic innovation. [PDF]

Front Immunol
Ding S, Wang H, Han Z, Hong S.
europepmc   +1 more source

The Role of MUC1 in Gastric Cancer Development. [PDF]

Cancers (Basel)
Radziejewska I.
europepmc   +1 more source

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Tissue Expression of Sialyl Tn Antigen in Gynecologic Tumors

Journal of Obstetrics and Gynaecology, 1995
AbstractObjective(s): To investigate tissue expression of Sialyl Tn antigen (STN) in gynecologic tumors, and to compare with its appearance in blood circulation.Methods: Surgical specimens were obtained from 24 patients with malignant gynecologic diseases, including 7 ovarian cancers, 13 cervical cancers, 3 endometrial cancers, and 1 vulval cancer ...
Fumitaka Numa, Shugo Nawata, S Nawata
exaly   +3 more sources

MUC2 mucin is a major carrier of the cancer-associated sialyl-Tn antigen in intestinal metaplasia and gastric carcinomas

Glycobiology, 2010
Changes in mucin protein expression and in glycosylation are common features in pre-neoplastic lesions and cancer and are therefore used as cancer-associated markers. De novo expression of intestinal mucin MUC2 and cancer-associated sialyl-Tn antigen are
Celso A. Reis, Raquel Almeida, Ulf Landegren   +2 more
exaly   +2 more sources

Tn and Sialyl‐Tn antigens in canine gastric tissues

Veterinary and Comparative Oncology, 2020
AbstractMalignant transformation is often associated with abnormal protein glycosylation expressed, amongst others, by the accumulation of simple mucin‐type carbohydrates namely Tn and Sialyl‐Tn (STn) antigens. These are usually limited in normal tissues and their increased expression has been associated with cancer progression and poor prognosis. This
Ana R. Flores, Isabel Lemos, Alexandra Rema, Marian Taulescu, Fernanda Seixas, Celso A. Reis, Fátima. Gärtner, Irina Amorim   +7 more
openaire   +2 more sources

Sialyl Tn antigen is an independent predictor of outcome in patients with gastric cancer

International Journal of Cancer, 1996
The prognostic value of the immunohistochemical expression of Sialyl Tn antigen (STn) was evaluated in 242 patients with gastric carcinoma. Formalin-fixed, paraffin-embedded specimens of gastric adenocarcinomas were stained with the monoclonal antibody C1282, produced by immunization with ovine submaxillary mucin (OSM).
M, Victorzon, S, Nordling, O, Nilsson, P J, Roberts, C, Haglund   +4 more
  +8 more sources