Results 21 to 30 of about 4,367 (168)
Frontiers in Immunology, 2022 BackgroundCarbohydrate Lewis antigens including sialyl Lewis A (sLeA), sialyl Lewis X (sLeX), Lewis X (LeX), and Lewis Y (LeY) are the commonest cell surface glycoconjugates that play pivotal roles in multiple biological processes, including cell ...
Zhi Ma +7 more
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Evidence for a lectin specific for sulfated glycans in the salivary gland of the malaria vector, Anopheles gambiae. [PDF]
PLoS ONE, 2014 Salivary gland homogenate (SGH) from the female mosquitoes Anopheles gambiae, An. stephensi, An. freeborni, An. dirus and An. albimanus were found to exhibit hemagglutinating (lectin) activity. Lectin activity was not found for male An.
Ivo M B Francischetti +3 more
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Lewis X and Sialyl Lewis X Glycosphingolipids.
Trends in Glycoscience and Glycotechnology, 1997 ルイスX (Lex) とシアリルルイスX (sLex) は、細胞接着に重要な血液型糖鎖抗原である。細胞膜において、LexとsLexは糖タンパク質やスフィンゴ糖脂質 (GSLs) 上に発現されていると思われる。糖脂質は、オリゴ糖鎖分子がセラミドという脂質の末端に共有結合で結ばれた複雑な高分子である。糖脂質に発現されたLexとsLex糖鎖は、糖タンパク質と同様に、単純なもの、高度にフコシル化されたもの、複合型のもの、分枝したもの、あるいは長鎖のものが存在する。LexとsLexの発現の発生段階における変化は、胎児の発達や器官形成に重要であると考えられる。好中球や血小板上のsLex抗原を持つスフィンゴ糖脂質は、血小板や好中球のローリングを制御していると思われる活性化された血管の内皮細胞に発現されるE ...
Cooling, Laura L. W. +2 more
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Staining of E-selectin ligands on paraffin-embedded sections of tumor tissue
BMC Cancer, 2018 Background The E-selectin ligands expressed by cancer cells mediate adhesion of circulating cancer cells to endothelial cells, as well as within tissue microenvironments important for tumor progression and metastasis.
Mylène A. Carrascal +9 more
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Molecules, 2022 Sialyl 6-sulfo Lewis X (6-sulfo sLeX) and its derivative sialyl 6-sulfo N-acetyllactosamine (LacNAc) are sialylated and sulfated glycans of sialomucins found in the high endothelial venules (HEVs) of secondary lymphoid organs. A component of 6-sulfo sLeX
Yoshiko Takeda-Uchimura +7 more
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PLoS ONE, 2009 BackgroundThe process of metastasis involves a series of steps and interactions between the tumor embolus and the microenvironment. Key alterations in adhesion molecules are known to dictate progression from the invasive to malignant phenotype followed ...
Salomé S Pinho +3 more
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Structural and Molecular Insights into AipA and OmpA: Key Drivers of Anaplasma phagocytophilum Host Cell Invasion [PDF]
Modern MedicineBackground: This analysis investigates invasion tactics of Anaplasma phagocytophilum which constitutes a gram-negative bacterial species that causes the tick-borne pathogen known as human granulocytic anaplasmosis (HGA).
Ali Adel DAWOOD +2 more
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Highly glycosylated MUC1 mediates high affinity L-selectin binding at the human endometrial surface
Journal of Nanobiotechnology, 2021 Background Sialyl-Lewis X/L-selectin high affinity binding interactions between transmembrane O-glycosylated mucins proteins and the embryo have been implicated in implantation processes within the human reproductive system.
Lewis W. Francis +13 more
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Human noroviruses recognize sialyl Lewis x neoglycoprotein [PDF]
Glycobiology, 2008 The carbohydrate binding characteristics of a norovirus GII.3 (Chron1) and a GII.4 (Dijon) strain were investigated using virus-like particles (VLPs) and saliva samples from 81 individuals genotyped for FUT2 (secretor) and FUT3 (Lewis) and phenotyped for ABO and Lewis blood groups. The two VLPs showed a typical secretor-gene-dependent binding and bound
Rydell, G.E. +6 more
openaire +3 more sources
Diagnostic Pathology, 2011 Background To elucidate relations of invasion of ulcerative colitis (UC)-associated carcinoma with its prognosis, the characteristics of invasive fronts were analyzed in comparison with sporadic colonic carcinomas.
Araki Kayo +6 more
doaj +1 more source