Results 111 to 120 of about 7,429 (165)

SIALYL-LEWIS-X ANTIGEN IMMUNOREACTION OF COLORECTAL-CANCER AND ITS RELATIONSHIP TO HEMATOGENOUS METASTASIS

Oncology Reports, 1994
The adhesion of cancer cells to endothelial cells of the target organ is one of the most important steps of hematogenous metastasis. Especially, sialyl Le(X) plays an important role in defining the metastasis. The expression of sialyl Le(X) antigen in colorectal cancer and its usefulness not only as an indicator of metastatic potential but also as a ...
A, Yamaguchi, M, Saitoh, T, Goi, M, Deguchi, K, Takeuchi, M, Maehara, K, Hirose, Y, Isobe, G, Nakagawara, S, Matsukawa   +9 more
openaire   +3 more sources

Binding of sialyl Lewis X antigen to lectin-like receptors on NK cells induces cytotoxicity and tyrosine phosphorylation of a 17-kDa protein

Biochimica Et Biophysica Acta - General Subjects, 2006
Koji Higai, Kojiro Matsumoto
exaly   +2 more sources

Increased expression of sialyl Lewisx antigen as a prognostic factor in patients with stage 0, I, and II gastric cancer

Cancer Letters, 2002
Kiyoyasu Fukushima, Terumitsu Sawai, Hiroyoshi Ayabe   +2 more
exaly   +2 more sources

Analysis of Serum Sialyl-Lewis x Antigen Levels in Acute Leukemias, Myelodysplastic Syndromes, Myeloproliferative Disorders and Malignant Lymphomas

Leukemia and Lymphoma, 2002
Yoshiki Terada, Yasutaka Aoyama, Ryousuke Yamamura   +2 more
exaly   +2 more sources

Sialyl-LewisX and related carbohydrate antigens in the prostate

Human Pathology, 1995
Alteration of cell surface carbohydrate antigens during malignant transformation is a well-known phenomenon observed in various tumors. In prostatic carcinoma, nearly total deletion of normally occurring ABO and type I-based Lewis antigens, Le(a) and Leb, has been observed in several studies.
S, Mårtensson, S A, Bigler, M, Brown, P H, Lange, M K, Brawer, S, Hakomori   +5 more
openaire   +2 more sources

Comparative evaluation of the prognostic value of MUC1, MUC2, sialyl‐Lewis^a and sialyl‐Lewis^x antigens in colorectal adenocarcinoma

Histopathology, 2002
Comparative evaluation of the prognostic value of MUC1, MUC2, sialyl‐Lewisa and sialyl‐Lewisx antigens in colorectal adenocarcinoma Aims: The significance of MUC1, MUC2 and sialylated Lewis blood group antigens as prognostic markers in colorectal adenocarcinoma was investigated in a large series of patients because previous investigations revealed ...
S E, Baldus, S P, Mönig, F-G, Hanisch, T K, Zirbes, U, Flucke, S, Oelert, G, Zilkens, B, Madejczik, J, Thiele, P M, Schneider, A H, Hölscher, H P, Dienes   +11 more
openaire   +2 more sources

Elevated plasma levels of a carbohydrate antigen, sialyl Lewis X, in liver diseases

Journal of Hepatology, 1993
A carbohydrate antigen, sialyl Lewis X (SLEX), is an inflammation-associated liver cell antigen, which is increasingly expressed as histological diagnosis progresses. A solid phase radioimmunoassay was developed to determine the plasma levels of this substance which were found to be elevated in about 70% of patients with liver disease, with no ...
T, Sunayama, Y, Okada, T, Tsuji
openaire   +2 more sources

Differential expression of Lewis^x and sialyl‐Lewis^x antigens in fetal human neural cells in culture

Journal of Neuroscience Research, 1994
AbstractLewisx is a cell‐surface carbohydrate antigen defined by the trisaccharide structure, Galβ 1→4 (Fucα 1→3) GlcNAc. Expression of Lewisx and sialyl‐Lewisx antigens in primary cell cultures isolated from fetal human brains of 12‐15 weeks gestation was investigated by double immunolabelling with antibodies against monomeric Lewisx (4C9), oligomeric
J, Satoh, S U, Kim
openaire   +2 more sources

The ruminant parasite Haemonchus contortus expresses an α1,3-fucosyltransferase capable of synthesizing the Lewis x and sialyl Lewis x antigens

Glycoconjugate Journal, 1998
Glycoproteins from the ruminant helminthic parasite Haemonchus contortus react with Lotus tetragonolobus agglutinin and Wisteria floribunda agglutinin, which are plant lectins that recognize alpha1,3-fucosylated GlcNAc and terminal beta-GalNAc residues, respectively.
R A, DeBose-Boyd, A K, Nyame, D P, Jasmer, R D, Cummings   +3 more
openaire   +2 more sources

Sialyl Lewis X (sLex):Biological functions, synthetic methods and therapeutic implications.

European journal of medicinal chemistry
Carbohydrates are shown to be crucial to several biological processes. They are essential mediators of cell-cell recognition processes. Among them, Sialyl Lewis X (sLex) is a very significant structure in the human body.
Leyu Tang, Jiaxu Zhang, Nassima Oumata, Nathalie Mignet, M. Sollogoub, Yongmin Zhang   +5 more
semanticscholar   +1 more source