Results 91 to 100 of about 17,841 (204)

Cellular Senescence, Inflammaging and Cardiovascular Disease

Immunological Reviews, Volume 337, Issue 1, January 2026.
ABSTRACT Aging is the most important yet unmodifiable risk factor for cardiovascular disease (CVD). As a result, targeting cardiovascular aging has emerged as a promising strategy to promote long‐term cardiovascular health. This review summarizes current knowledge on the effects of aging within the cardiovascular system as well as systemic processes ...
Lukas Zanders, Denada Arifaj, Julian U. G. Wagner, Stefanie Dimmeler   +3 more
wiley   +1 more source

Prognostically Significant Glycan Profiles of Clear Cell Renal Cell Carcinoma Identified by Integrated Glycome–Methylome Analysis

Pathology International, Volume 76, Issue 1, January 2026.
Comprehensive glycomics analysis and genome‐wide DNA methylation analysis using tissue samples of clear cell renal cell carcinoma (ccRCC) have revealed that the glycan profile, including “immature” N‐type glycans, may be attributable to epigenetic regulation of glycogenes.
Yoshiko Kitazume, Eri Arai, Mao Fujimoto, Kentaro Ohara, Atsushi Matsuda, Shuichi Kakuda, Hiroyuki Fujimoto, Akiko Miyagi Maeshima, Nobuyoshi Hiraoka, Teruhiko Yoshida, Atsushi Kuno, Yae Kanai   +11 more
wiley   +1 more source

Recombinant Sialyltransferase Infusion Mitigates Infection-Driven Acute Lung Inflammation

Frontiers in Immunology, 2019
Inappropriate inflammation exacerbates a vast array of chronic and acute conditions with severe health risks. In certain situations, such as acute sepsis, traditional therapies may be inadequate in preventing severe organ damage or death.
Mehrab Nasirikenari, Amit A. Lugade, Sriram Neelamegham, Zhongwei Gao, Kelley W. Moremen, Paul N. Bogner, Yasmin Thanavala, Joseph T. Y. Lau   +7 more
doaj   +1 more source

Lactosylceramide molecular species specificity of rat liver CMP-N-acetylneuraminate:lactosylceramide sialyltransferase.

Journal of Lipid Research, 1989
Six naturally occurring and three synthetic molecular species of lactosylceramide (LacCer) were used to examine the molecular species specificity of CMP-N-acetylneuraminate:lactosylceramide alpha 2,3-sialyltransferase in a Golgi-rich fraction of rat ...
H Kadowaki, L A Symanski, K E Rys-Sikora, R S Koff   +3 more
doaj   +1 more source

Cleavage of ST6Gal I by Radiation-Induced BACE1 Inhibits Golgi-Anchored ST6Gal I-Mediated Sialylation of Integrin β1 and Migration in Colon Cancer Cells

Radiation Oncology, 2012
Background Previously, we found that β-galactoside α2,6-sialyltransferase (ST6Gal I), an enzyme that adds sialic acids to N-linked oligosaccharides of glycoproteins and is frequently overexpressed in cancer cells, is up-regulated by ionizing radiation ...
Lee Minyoung, Park Jung-Jin, Ko Young-Gyu, Lee Yun-Sil   +3 more
doaj   +1 more source

Anterior Olfactory Nucleus [PDF]

, 2008
This report contains a gene expression summary of the anterior olfactory nucleus (AON), derived from the Allen Brain Atlas (ABA) in situ hybridization mouse data set.
Allen Institute for Brain Science, Angela L. Guillozet-Bongaarts, Beth M. Solan, Lydia L. Ng   +3 more
core   +2 more sources

In vitro synthesis of colominic acid by membrane‐bound sialyltransferase of Escherichia coli K‐235 [PDF]

, 1989
Ana I. Ortiz, Ángel Reglero, Leandro B. Rodrı́guez-Aparicio, José M. Luengo   +3 more
openalex   +1 more source

Triple-negative and HER2-overexpressing breast cancer cell sialylation impacts tumor microenvironment T-lymphocyte subset recruitment: a possible mechanism of tumor escape

Cancer Management and Research, 2018
Christian Garbar,1,2 Corinne Mascaux,1,2 Yacine Merrouche,1,2 Armand Bensussan3 1Biopathology Department, Institut Jean Godinot – Unicancer, Reims, France; 2DERM-I-C EA7319, Université de Reims Champagne – Ardenne, Reims, France ...
Garbar C, Mascaux C, Merrouche Y, Bensussan A   +3 more
doaj  

Development of a novel method to evaluate sialylation of glycoproteins and analysis of gp96 sialylation in Hela, SW1990 and A549 cell lines

Biological Research, 2015
BACKGROUND: Glycoproteins play a critical role in the cellular activities of eukaryotes. Sialic acid is typically the outermost monosaccharide of glycolipids and glycoproteins, and is necessary for normal development.
Yangui Liang, Qiang Hua, Pengwei Pan, Jie Yang, Qi Zhang   +4 more
doaj   +1 more source

MUC1 in human and murine mammary carcinoma cells decreases the expression of core 2  1,6-N-acetylglucosaminyltransferase and  -galactoside  2,3-sialyltransferase [PDF]

, 2012
A. Solatycka, Tomasz B. Owczarek, Friedrich Piller, Véronique Piller, Bartosz Puła, Łukasz Wojciech, Marzenna Podhorska‐Okołów, Piotr Dzięgiel, Maciej Ugorski   +8 more
openalex   +1 more source