Results 71 to 80 of about 17,841 (204)

HID-1 controls formation of large dense core vesicles by influencing cargo sorting and trans-Golgi network acidification [PDF]

, 2017
Large dense core vesicles (LDCVs) mediate the regulated release of neuropeptides and peptide hormones. They form at the trans-Golgi network (TGN), where their soluble content aggregates to form a dense core, but the mechanisms controlling biogenesis are ...
Asensio, Cedric S, Burns, Christian, Chen, Lan, de Leeuw, Noah F, Fitzpatrick, James A. J., Hosford, Bethany, Hummer, Blake H, Joens, Matthew S   +7 more
core   +2 more sources

Androgen-regulated transcriptional control of sialyltransferases in prostate cancer cells. [PDF]

PLoS ONE, 2012
The expression of gangliosides is often associated with cancer progression. Sialyltransferases have received much attention in terms of their relationship with cancer because they modulate the expression of gangliosides.
Koji Hatano, Yasuhide Miyamoto, Masaki Mori, Keisuke Nimura, Yasutomo Nakai, Norio Nonomura, Yasufumi Kaneda   +6 more
doaj   +1 more source

Stereoisomer‐specific reprogramming of a bacterial flagellin sialyltransferase [PDF]

, 2023
Nicolas Kint, Thomas Dubois, Patrick H. Viollier   +2 more
openalex   +1 more source

Expression patterns of α2,3-Sialyltransferase I and α2,6-Sialyltransferase I in human cutaneous epithelial lesions

European Journal of Histochemistry, 2013
Skin tumors have become one of the most common cancers in the world and their carcinogenesis is frequently associated with altered glycosylation patterns. The aberrant sialylation, a type of glycosylation, can mediate pathophysiological key events during
S.A. Ferreira, J.L.A. Vasconcelos, R.C.W.C. Silva, C.L.B. Cavalcanti, C.L. Bezerra, M.J.B.M. Rêgo, E.I.C. Beltrão   +6 more
doaj   +1 more source

ST3GAL1 is a target of the SOX2-GLI1 transcriptional complex and promotes melanoma metastasis through AXL

Nature Communications, 2020
Understanding the molecular events controlling melanoma progression are necessary to find improved therapeutics. Here, the authors report oncogenic SOX2-GLI1 transcriptional complex to drive melanoma invasion through the induction of the ...
Silvia Pietrobono, Giulia Anichini, Cesare Sala, Fabrizio Manetti, Luciana L. Almada, Sara Pepe, Ryan M. Carr, Brooke D. Paradise, Jann N. Sarkaria, Jaime I. Davila, Lorenzo Tofani, Ilaria Battisti, Giorgio Arrigoni, Li Ying, Cheng Zhang, Hu Li, Alexander Meves, Martin E. Fernandez-Zapico, Barbara Stecca   +18 more
doaj   +1 more source

Acute phase inflammation is characterized by rapid changes in plasma/peritoneal fluid N-glycosylation in mice. [PDF]

, 2016
To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked Files.
Freysdottir, Jona, Giera, Martin, Hardardottir, Ingibjörg, Hipgrave Ederveen, Agnes L, Ioan-Facsinay, Andreea, Jansen, Bas C, Jónasdóttir, Hulda S, Reiding, Karli R, Rombouts, Yoann, Wuhrer, Manfred   +9 more
core   +1 more source

Accumulation of GD1α Ganglioside in MDA-MB-231 Breast Cancer Cells Expressing ST6GalNAc V

Molecules, 2015
α-Series gangliosides define a particular sub-class of glycosphingolipids containing sialic acid α2,6-linked to GalNAc residue that was isolated as a minor compound from the brain.
Sandy Vandermeersch, Jorick Vanbeselaere, Clément P. Delannoy, Aurore Drolez, Caroline Mysiorek, Yann Guérardel, Philippe Delannoy, Sylvain Julien   +7 more
doaj   +1 more source

De Novo Assembly of Mud Loach (Misgurnus anguillicaudatus) Skin Transcriptome to Identify Putative Genes Involved in Immunity and Epidermal Mucus Secretion [PDF]

, 2013
Fish skin serves as the first line of defense against a wide variety of chemical, physical and biological stressors. Secretion of mucus is among the most prominent characteristics of fish skin and numerous innate immune factors have been identified in ...
Cui, ZB (reprint author), Chinese Acad Sci, Inst Hydrobiol, Key Lab Aquat Biodivers & Conservat, Wuhan, Hubei, Peoples R China., Cui, Zongbin, Li, Qing, Li, Tao, Long, Yong, Song, Guili, Zhou, Bolan   +6 more
core   +1 more source

A Golgi-associated redox switch regulates catalytic activation and cooperative functioning of ST6Gal-I with B4GalT-I

Redox Biology, 2019
Glycosylation, a common modification of cellular proteins and lipids, is often altered in diseases and pathophysiological states such as hypoxia, yet the underlying molecular causes remain poorly understood.
Antti Hassinen, Fawzi Khoder-Agha, Elham Khosrowabadi, Daniela Mennerich, Deborah Harrus, Maxence Noel, Elitsa Y. Dimova, Tuomo Glumoff, Anne Harduin-Lepers, Thomas Kietzmann, Sakari Kellokumpu   +10 more
doaj   +1 more source

The Cytoplasmic Droplets of Rat Epididymal Spermatozoa Show Diminution of Glycosyl Transferases During Spermatozoa Epididymal Maturation

McGill Journal of Medicine, 2020
The cytoplasmic droplet of the epididymal spermatozoon is a small localized outpouching of cytoplasm of the tail and is of unknown significance. Electron microscopy revealed flattened saccular elements of almost exclusive membranous components.
Peter Chan
doaj   +1 more source