Results 91 to 100 of about 11,605 (209)

ST3Gal.I sialyltransferase relevance in bladder cancer tissues and cell lines

BMC Cancer, 2009
Background The T antigen is a tumor-associated structure whose sialylated form (the sialyl-T antigen) involves the altered expression of sialyltransferases and has been related with worse prognosis.
Calais Fernando M, Ligeiro Dário, Crespo Hélio J, Malagolini Nadia, Correia Manuela, Videira Paula A, Trindade Helder, Dall'Olio Fabio   +7 more
doaj   +1 more source

Novel Zebrafish Mono-α2,8-sialyltransferase (ST8Sia VIII): An Evolutionary Perspective of α2,8-Sialylation [PDF]

, 2019
International audienceThe mammalian mono-α2,8-sialyltransferase ST8Sia VI has been shown to catalyze the transfer of a unique sialic acid residues onto core 1 O-glycans leading to the formation of di-sialylated O-glycosylproteins and to a lesser extent ...
Harduin-Lepers, Anne, Lion, Cedric, Teppa, Roxana Elin, Chang, Lan-Yi, Cogez, Virginie, Pierre-André Gilormini, Delannoy, Philippe, Petit, Daniel, Philippe Delannoy, Decloquement, Mathieu, Chang, Lan Yi, Cédric Lion, Khoo, Kay,, Gilormini, Pierre-André, Elin Teppa, Christophe Biot, Harduin Lepers, Anne, Yann Guérardel, Khoo, Kay, Hooi, Anne-Marie Mir, Daniel Petit, Khoo, Kay Hooi, Biot, Christophe, Guerardel, Yann, Virginie Cogez, Mir, Anne Marie, Noel, Maxence, Mathieu Decloquement, Lan-Yi Chang, Maxence Noel, Anne Harduin-Lepers, Gilormini, Pierre André, Mir, Anne-Marie, Kay Hooi Khoo, Teppa, Elin   +34 more
core   +1 more source

Prognostic value of Tumoral Sialyltransferase Expression and Circulating E-Selectin Concentrations in Node-Negative Breast Cancer Patients

The International Journal of Biological Markers, 2003
Aims and Background A crucial step in the metastatic process is the interaction between the endothelial molecule E-selectin and its tumoral ligands sialyl-Lewisx and sialyl-Lewis a .
M. Hebbar, M.-A. Krzewinski-Recchi, L. Hornez, A. Verdière, A. Harduin-Lepers, J. Bonneterre, P. Delannoy, J.-P. Peyrat   +7 more
doaj   +1 more source

Decreasing the sialidase activity of multifunctional Pasteurella multocidaα2–3-sialyltransferase 1 (PmST1) by site-directed mutagenesis

, 2011
Pasteurella multocida α2-3-sialyltransferase 1 (PmST1) is a multifunctional enzyme which has α2-6-sialyltransferase, α2-3-sialidase, and α2-3-trans-sialidase activities in addition to its major α2-3-sialyltransferase activity.
Khedri, Zahra, Li, Yanhong, Yu, Hai, Chen, Xi, Hai Yu, Xi Chen, Zahra Khedri, Go Sugiarto, Yanhong Li, Lau, Kam, Sugiarto, Go, Le, Diem-Thuy, Diem-Thuy Le, Kam Lau   +13 more
core   +1 more source

Effect of desipramine on a glycoprotein sialyltransferase activity in C6 cultured glioma cells.

, 1990
International audienceThe tricyclic antidepressant desipramine, when added to culture medium, gave rise in C6 rat glioma cells to a decrease of the activity of the enzyme asialofetuin sialyltransferase.
Broquet, P., Baubichon-Cortay, H., Peschard, Mj, George, P., Louisot, P.   +4 more
core   +2 more sources

Sialyltransferase-Based Chemoenzymatic Histology for the Detection of N- and O‑Glycans

, 2018
Profiling specific glycans in histopathological samples is hampered by the lack of selective and sensitive tools for their detection. Here, we report on the development of chemoenzymatic histology of membrane polysaccharide (CHoMP)-based methods for the ...
Wei Li (7081), Peng Wu (210686), Lu Meng (289653), Kelley W. Moremen (2077327), Xiaomeng Hou (4412476), Aime Lopez Aguilar (4585366)   +5 more
core   +1 more source

Stromal cells modulate innate immune cell phenotype and function in colorectal cancer via the Sialic acid/Siglec axis

Journal for ImmunoTherapy of Cancer
Background The immunosuppressive tumor microenvironment reduces immune response effectiveness in stromal-rich tumors, including consensus molecular subtype 4 colorectal cancer (CRC).
Seán O Hynes, Laurence J Egan, Philip D Dunne, Oliver Treacy, Hannah Egan, Thomas Ritter, Margaret Sheehan, Aideen E Ryan, Linda Howard, Li Peng, Michael O’Dwyer, Lizhi Cao, Jenny Che, Shania M Corry, Niamh A Leonard, Aoife Canney, Eileen Reidy, Aoise O’Neill, Kevin Culligan, Norashikin Zakaria, Courtney Bull, Clodagh O’Meara, Anastasija Walsh, Aisling M Hogan   +23 more
doaj   +1 more source

occurrence of sialyltransferase activity in the synaptosomal membranes prepared from calf brain

, 1980
The possible occurrence of sialyltransferase activity in the plasma membranes surrounding nerve endings (synaptosomal membranes) was studied, using calf brain cortex. The synaptosomal membranes were prepared by an improved procedure which provided: (a) a
A. Lombardo, A. Preti, G. Tettamanti, L. Caimi, A. Fiorilli   +4 more
core   +1 more source

Overexpression of sialyltransferase CMP-sialic Acid : Galbeta1,3GalNAc-R alpha6-sialyltransferase is related to poor patient survival in human colorectal carcinomas

, 2001
Thomsen-Friedenreich (TF)-related blood group antigens, such as TF, Tn, and their sialylated variants, belong to a family of tumor-associated carbohydrates.
Haensch, W., Karsten, U., Schlag, P.M., Kemmner, W., Franke, G., Schneider, F., Gretschel, S.   +6 more
core  

Effect of Acute and Chronic Ethanol Administration on Rat Liver α 2,6‐Sialyltransferase Activity Responsible for Sialylation of Serum Transferrin

, 1989
The effect of a single administration and a 6‐week treatment with ethanol on rat liver sialyltransferase activity towards asialoglycoproteins and N‐acetyllactosamine (Galβ91,4GlcNAc) was studied.
Cessi C., Malagolini N., Serafini F., Dall'Olio F.   +3 more
core   +1 more source