Results 131 to 140 of about 94,881 (302)
ABSTRACT Objective Patients with burning mouth syndrome (BMS) suffer from oral pain in the absence of oral lesions. Although less frequently, they may also experience extraoral symptoms that are not readily apparent to clinicians. This study aimed to systematically assess the prevalence of associated extraoral symptoms and comorbid disorders in BMS ...
João Paulo Gonçalves de Paiva +6 more
wiley +1 more source
Protein S Enhances the Phagocytosis of Phosphatidylserine-Exposing Erythrocytes: Implications in Sickle Cell Disease. [PDF]
ABSTRACT The major anticoagulant Protein S (PROS1) also contributes to the phagocytosis of apoptotic cells by bridging exposed phosphatidylserine (PtdSer) to the MerTK receptor on macrophages (efferocytosis). Whether PROS1 is involved in the splenic clearance of PtdSer‐positive senescent and altered erythrocytes such as erythrocyte ghosts (eryghosts ...
Auditeau C +26 more
europepmc +2 more sources
Abstract Orthotopic allograft transplantation (OAT) is a significant approach to addressing organ failure. However, persistent immune responses to the allograft affect chronic rejection, which induces OAT vasculopathy (OATV) and organ failure. Porphyromonas gingivalis can infiltrate remote organs via the bloodstream, thereby intensifying the severity ...
Chien‐Sung Tsai +7 more
wiley +1 more source
MANAGEMENT OF CHILDREN WITH SICKLE CELL DISEASE IN EUROPE: CURRENT SITUATION AND FUTURE PERSPECTIVES
Sickle cell disease (SCD) is the most common haemoglobinopathy worldwide and its frequency has steadily increased in Europe in the past decades. SCD is a complex multisystem disorder characterised by chronic haemolytic anaemia, vaso-occlusive crisis, and
Raffaella Colombatti, Laura Sainati
doaj
Landscape of Current Transplant Infectious Disease Training Programs
ABSTRACT Background Transplant infectious disease (TID) training is not accredited by the Accreditation Council for Graduate Medical Education (ACGME) and is not standardized. Prior surveys of the training landscape in TID have focused on fellow responses; we sought description of programs from program directors and coordinators. Methods Along with the
Michael J. Scolarici +7 more
wiley +1 more source
Genotype Differences and Hydroxyurea Utilization Among Adults With Moderate to Severe Sickle Cell Disease. [PDF]
ABSTRACT Backgrounds Hydroxyurea (HU) remains underutilized in adults with sickle cell disease (SCD) despite proven benefits. Current HU guidelines primarily target sickle cell anemia (SCA), overlooking other genotypes. Objectives This study examined HU utilization patterns across genotypes among adults considered to have moderate to severe SCD ...
Cheng SH +4 more
europepmc +2 more sources
Perspectives in genomics and sickle cell disease therapeutics [PDF]
Ambroise Wonkam
openalex +1 more source
Malaria polymerase chain reaction (PCR) testing is more sensitive than conventional diagnostics. Routine PCR screening of at‐risk asymptomatic hematopoietic cell donors and transplant candidates may prevent unnecessary deferrals or treatment. In our experience, PCR negativity during screening or after treatment supports donor/candidate eligibility ...
Mary M. Czech +5 more
wiley +1 more source
Hemolysis inhibits humoral B-cell responses and modulates alloimmunization risk in patients with sickle cell disease [PDF]
Mouli Pal +11 more
openalex +1 more source

