Results 11 to 20 of about 429,758 (251)
Fetal Hemoglobin in Sickle Cell Anemia.
Blood, 2020 Fetal hemoglobin (HbF) can blunt the pathophysiology, temper the clinical course and offer prospects for curative therapy of sickle cell disease. This review focuses on: 1.
M. Steinberg
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Asymmetric sickle cell retinopathy in a patient with sickle cell hemoglobin D disease: A case report
Indian Journal of Ophthalmology. Case Reports, 2023 Sickle cell disease (SCD), the most commonly inherited hemoglobinopathy, can result in vision loss due to sickle cell retinopathy (SCR), vascular occlusions, and retinal atrophy.
Anil B Gangwe +5 more
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The Microrheology of Sickle Hemoglobin Gels [PDF]
Biophysical Journal, 2010 Sickle cell disease is a rheological disease, yet no quantitative rheological data exist on microscopic samples at physiological concentrations. We have developed a novel method for measuring the microrheology of sickle hemoglobin gels, based on magnetically driven compression of 5- to 8-microm-thick emulsions containing hemoglobin droplets ...
Zakharov, Mikhail N. +3 more
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BMC Biology, 2023 Background Intracellular hemoglobin polymerization has been supposed to be the major determinant for the elevated rigidity/stiffness of sickle erythrocytes from sickle cell anemia (SCA) patients.
Kun Wang +5 more
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Journal of Applied Hematology, 2022 BACKGROUND: Sickle cell disease and its variants result from an abnormal hemoglobin, hemoglobin S (HbS), caused by a single point mutation in the Beta-Globin gene.
Hareem Alam, Natasha Ali
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Nonideality and the Nucleation of Sickle Hemoglobin [PDF]
Biophysical Journal, 2000 The homogeneous and heterogeneous nucleation kinetics of sickle hemoglobin (HbS) have been studied for various degrees of solution crowding by substitution of cross-linked hemoglobin A, amounting to 50% of the total hemoglobin. By cross-linking hemoglobin A, hybrid formation between hemoglobin A and hemoglobin S was prevented, thus simplifying the ...
Ivanova, Maria +4 more
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Thermal properties of normal and sickled hemoglobin protein
Bibechana, 2021 Thermodynamic properties of sickled and normal hemoglobin protein are considered within the framework of classical molecular dynamics. Here we have studied the specific heat capacity and RMSD (Root Mean Square Deviation) of both types of hemoglobin ...
Jhulan Powrel, Narayan P Adhikari
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Frontiers in Medicine, 2022 Sickle cell disease (SCD) is a heterogeneous group of inherited disorders characterized by the production of sickle hemoglobin which is less soluble than an adult or fetal hemoglobin.
Awni Alshurafa, Mohamed A. Yassin
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Fetal Hemoglobin in Sickle Hemoglobinopathies: High HbF Genotypes and Phenotypes
Journal of Clinical Medicine, 2020 Fetal hemoglobin (HbF) usually consists of 4 to 10% of total hemoglobin in adults of African descent with sickle cell anemia. Rarely, their HbF levels reach more than 30%.
M. Steinberg
semanticscholar +1 more source