Results 21 to 30 of about 25,303 (208)
Haematologica, 2012 Background Little is known about the effects of blood rheology on the occurrence of acute chest syndrome and painful vaso-occlusive crises in children with sickle cell anemia and hemoglobin SC disease.Design and Methods To address this issue, steady ...
Yann Lamarre +13 more
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THE STATE OF HEMOGLOBIN IN SICKLED ERYTHROCYTES [PDF]
The Journal of Experimental Medicine, 1966 Electron microscopic and other evidence have provided support for the hypothesis that the sickling phenomenon is due to the intracellular formation of long slender crystals of reduced sickle hemoglobin. The rapid growth of these crystals causing tenting of the cell membrane is responsible for the bizarre distortion of the erythrocytes and presumably ...
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Sickle Retinopathy in a Person with Hemoglobin S/New York Disease
Case Reports in Genetics, 2012 A patient who presented with sickle retinopathy and hemoglobin electrophoresis results compatible with sickle cell trait was found, on further investigation, to be a compound heterozygote with hemoglobin S and hemoglobin New York disease.
Donovan Calder +4 more
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Revista Brasileira de Hematologia e Hemoterapia, 2014 Objective: The aim of the present study was to characterize sickle cell disease retinopathy in children and teenagers from Bahia, the state in northeastern Brazil with the highest incidence and prevalence of sickle cell disease.
Dayse Cury de Almeida Oliveira +5 more
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Acta Médica Portuguesa, 2017 Introduction: The benefits of manual versus automated red blood cell exchange have rarely been documented and studies in young sickle cell disease patients are scarce. We aim to describe and compare our experience in these two procedures.
Carlos Escobar +9 more
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The post-mortem diagnosis of vasocclusive crisis in sickle cell disease
Autopsy and Case Reports, 2014 Sickle cell disease (SCD) comprises a group of genetic blood disorders that affect the hemoglobin molecular structure, and in some cases, the association with hemoglobin synthesis.
Varsha Bhatia +2 more
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A clinico-hematological study of sickle cell disease among adult patients in Makkah, Saudi Arabia. [PDF]
Al-Azhar International Medical Journal, 2023 Background: Sickle cell disease is an autosomal recessive disease characterized by aberrant production of hemoglobin S (HbS). The clinical picture includes hemolytic anemia, vascular occlusion events, acute and persistent pain, and varied organ damage ...
Ahmad Arbaeen
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Structure of Sickled Erythrocytes and of Sickle-Cell Hemoglobin Fibers [PDF]
Proceedings of the National Academy of Sciences, 1973 Deoxyhemoglobin from patients homozygous for sickle-cell anemia (deoxyhb S) aggregates into long straight fibers. These may extend through most of the length of the sickled cell, forming either square or hexagonally packed bundles with lattice constants of 170-180 Å. Each fiber is a tube made up of six thin filaments, which are wound around the tubular
J T, Finch +3 more
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Prevalence of hemoglobin abnormalities in an apparently healthy population in Benin
Hematology, Transfusion and Cell Therapy, 2020 Background: Sickle cell disease is the most common monogenic disorder in humans and is a major public health concern in sub-Saharan Africa. In Benin, the prevalence of sickle cell disease is estimated to be 4.8%.
Alban Zohoun +3 more
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Revista Brasileira de Hematologia e Hemoterapia, 2012 BACKGROUND: Sickle cell disease is a hemoglobinopathy characterized by hemolytic anemia, increased susceptibility to infections and recurrent vaso-occlusive crises that reduces the quality of life of sufferers.
Darcielle Bruna Dias Elias +5 more
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