Results 21 to 30 of about 46,454 (250)
Sickle Retinopathy in a Person with Hemoglobin S/New York Disease
Case Reports in Genetics, 2012 A patient who presented with sickle retinopathy and hemoglobin electrophoresis results compatible with sickle cell trait was found, on further investigation, to be a compound heterozygote with hemoglobin S and hemoglobin New York disease.
Donovan Calder +4 more
doaj +1 more source
Acta Médica Portuguesa, 2017 Introduction: The benefits of manual versus automated red blood cell exchange have rarely been documented and studies in young sickle cell disease patients are scarce. We aim to describe and compare our experience in these two procedures.
Carlos Escobar +9 more
doaj +1 more source
The post-mortem diagnosis of vasocclusive crisis in sickle cell disease
Autopsy and Case Reports, 2014 Sickle cell disease (SCD) comprises a group of genetic blood disorders that affect the hemoglobin molecular structure, and in some cases, the association with hemoglobin synthesis.
Varsha Bhatia +2 more
doaj +1 more source
The Evolving Pharmacotherapeutic Landscape for the Treatment of Sickle Cell Disease. [PDF]
, 2020 Sickle cell disease (SCD) is an extremely heterogeneous disease that has been associated with global morbidity and early mortality. More effective and inexpensive therapies are needed.
Ballas, Samir K
core +1 more source
Haemoglobinopathies and newborn haemoglobinopathy screening in Germany. [PDF]
, 2009 Germany has been an immigration country since the early 1950s. In December 2007, 6.7 million non-German citizens lived in the country. However, the total number of citizens with a migration background is 15–20 million, about 9 million of whom come ...
Dickerhoff, R. +2 more
core +1 more source
Prevalence of hemoglobin abnormalities in an apparently healthy population in Benin
Hematology, Transfusion and Cell Therapy, 2020 Background: Sickle cell disease is the most common monogenic disorder in humans and is a major public health concern in sub-Saharan Africa. In Benin, the prevalence of sickle cell disease is estimated to be 4.8%.
Alban Zohoun +3 more
doaj +1 more source
Nutritional status of young children with inherited blood disorders in western Kenya. [PDF]
, 2014 To determine the association between a range of inherited blood disorders and indicators of poor nutrition, we analyzed data from a population-based, cross-sectional survey of 882 children 6–35 months of age in western Kenya.
Ruth, LJ +4 more
core +1 more source
Comorbidities in aging patients with sickle cell disease. [PDF]
, 2018 Sickle cell disease (SCD) in general and sickle cell anemia in particular is a highly complex disorder both at the molecular and clinical levels. Although the molecular lesion is a single-point mutation, the sickle gene is pleiotropic in nature causing ...
Ballas, Samir K.
core +2 more sources
Revista Brasileira de Hematologia e Hemoterapia, 2012 BACKGROUND: Sickle cell disease is a hemoglobinopathy characterized by hemolytic anemia, increased susceptibility to infections and recurrent vaso-occlusive crises that reduces the quality of life of sufferers.
Darcielle Bruna Dias Elias +5 more
doaj +1 more source
Impact of Isovolemic Hemodilution-Red Cell Exchange on Health-Related Quality of Life in Patients With Sickle Cell Disease: A Pilot Study. [PDF]
J Clin ApherABSTRACT Sickle cell disease (SCD) negatively affects health‐related quality of life (HRQoL). Isovolemic hemodilution (IHD) red‐cell exchange (RCE) is being increasingly used to treat SCD‐related complications, but its impact on HRQoL has not been characterized.
Murray A +4 more
europepmc +2 more sources