Results 291 to 300 of about 821,630 (331)

Behavioral Domain-Specific Effects of Positive Modulation of α5 and α6 GABA_A Receptors in a Rat Double-Hit Stress Model. [PDF]

Pharmacol Res Perspect
Đorović Đ, Aranđelović J, Ivanović J, Jezdić K, Batinić B, Sharmin D, Mondal P, Cook JM, Savić MM.   +8 more
europepmc   +1 more source

Modulation of Corticotropin-Releasing Hormone Receptor Expression During In Vitro Keratinocyte Differentiation. [PDF]

Curr Issues Mol Biol
Martins CA, Lesink S, Roux A, Collet G, Daniellou R.   +4 more
europepmc   +1 more source

Analyses of receptor binding specificity of highly pathogenic avian influenza A (H5N1) viruses isolated from felines in South Korea, 2023. [PDF]

Virulence
Son DH, Balupuri A, Nam JH, Kim IH, Choi YJ, An BM, Kim JM, Kim EJ, Kang NS.   +8 more
europepmc   +1 more source

Characterization of Novel Sigma Receptor Ligands Derived from Multicomponent Reactions as Efficacious Treatments for Neuropathic Pain. [PDF]

Pharmaceuticals (Basel)
Shinouchi R, Turgutalp B, Ople RS, Eans SO, Williams AK, Hammond HR, Varadi A, Dardashti RN, Majumdar S, McLaughlin JP.   +9 more
europepmc   +1 more source

SARS-CoV-2 NSP6 reduces autophagosome size and affects viral replication via sigma-1 receptor

Cuiling Zhang, Qiwei Jiang, Zirui Liu, Nan Li, Zhuo Hao, Gaojie Song, Dapeng Li, Minghua Chen, Lisen Lin, Yan Liu, Xiao Li, Chao Shang, Yiquan Li   +12 more
openalex   +1 more source

DNAM-1 mediates NK-cell activation and host-pathogen interaction via direct binding to fungal cell wall proteases. [PDF]

Commun Biol
Natasha F, Heilig L, Helmerich DA, Luther C, Springer J, Kar B, Drobny M, Kasper L, Schuh C, Dittrich M, Hube B, Dandekar T, Sauer M, Löffler J, Terpitz U.   +14 more
europepmc   +1 more source

Sigma-1 Receptors & Disease (S1RaD) 2025

Geriatric Pharmacology
openaire   +1 more source

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The sigma 1 receptor: A local media influencer

Cell Calcium, 2021
The endoplasmic reticulum (ER) Ca2+ store contains many rapidly differentiable subdomains with specialized signaling properties. Recent work highlights how an integral ER membrane protein - the sigma 1 receptor (S1R) - nucleates local formation of cholesterol-rich ER subdomains.
Claudia M, Rohr, Jonathan S, Marchant
openaire   +2 more sources

Sigma-1 receptor and inflammatory pain

Inflammation Research, 2015
The sigma-1 receptor (Sig-1R) is a unique ligand-regulated molecular chaperone that interacts with several protein targets such as G protein-coupled receptors and ion channels to modulate their activity. Sig-1R is located in areas of the central and peripheral nervous system that are key to pain control.
Georgia, Gris, Enrique José, Cobos, Daniel, Zamanillo, Enrique, Portillo-Salido   +3 more
openaire   +2 more sources

Sigma-1 Receptor and Pain

2017
There is a critical need for new analgesics acting through new mechanisms of action, which could increase the efficacy respect to existing therapies and/or reduce their unwanted effects. Current preclinical evidence supports the modulatory role of the sigma-1 receptor (σ1R) in nociception, mainly based on the pain-attenuated phenotype of σ1R knockout ...
Manuel, Merlos, Luz, Romero, Daniel, Zamanillo, Carlos, Plata-Salamán, José Miguel, Vela   +4 more
openaire   +2 more sources