Results 41 to 50 of about 1,167,503 (297)

The alternative sigma factor SigB of Corynebacterium glutamicum modulates global gene expression during transition from exponential growth to stationary phase

open access: yes, 2007
Larisch C, Nakunst D, Hueser AT, Tauch A, Kalinowski J. The alternative sigma factor SigB of Corynebacterium glutamicum modulates global gene expression during transition from exponential growth to stationary phase. BMC Genomics. 2007;8(1): 4.Background:
Andrea T Hüser   +14 more
core   +1 more source

A role for sigma factor ?(E) in Corynebacterium pseudotuberculosis resistance to nitric oxide/peroxide stress

open access: yes, 2012
Pathogenic intracellular bacteria can respond to antimicrobial mechanisms of the host cell through transient activation of stress-responsive genes by alternative sigma (?) factors of the RNA polymerase.
Scrivens, James H.   +37 more
core   +1 more source

Transcriptional regulation by sigma factor phosphorylation in bacteria

open access: yes, 2020
Alternative sigma factors regulate the activity of RNA polymerases under specific conditions and are regulated through various mechanisms, most of which depend on anti-sigma factors to regulate their on/off status.
Iyer, S.   +7 more
core   +1 more source

Anti-sigma factors

open access: yesCurrent Opinion in Microbiology, 1999
Anti-sigma factors modulate the expression of numerous regulons controlled by alternative sigma factors. Anti-sigma factors are themselves regulated by either secretion from the cell (i.e. FlgM export through the hook-basal body), sequestration by an anti-anti-sigma (i.e.
openaire   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Expression of the Arabidopsis Sigma Factor SIG5 Is Photoreceptor and Photosynthesis Controlled

open access: yesPlants, 2014
Two collections of Arabidopsis GAL4 enhancer trap lines were screened for light-intensity dependent reporter gene activation. Line N9313 was isolated for its strong light-intensity regulation.
Marina Mellenthin   +3 more
doaj   +1 more source

Spatial organization of different sigma factor activities and c-di-GMP signalling within the three-dimensional landscape of a bacterial biofilm [PDF]

open access: yesOpen Biology, 2018
Bacterial biofilms are large aggregates of cells embedded in an extracellular matrix of self-produced polymers. In macrocolony biofilms of Escherichia coli, this matrix is generated in the upper biofilm layer only and shows a surprisingly complex ...
Gisela Klauck   +3 more
doaj   +1 more source

Structural Analysis of Bacillus subtilis Sigma Factors

open access: yesMicroorganisms, 2023
Bacteria use an array of sigma factors to regulate gene expression during different stages of their life cycles. Full-length, atomic-level structures of sigma factors have been challenging to obtain experimentally as a result of their many regions of ...
Katherine M. Collins   +6 more
doaj   +1 more source

Novel sigmaB regulation modules of Gram-positive bacteria involve the use of complex hybrid histidine kinases.

open access: yes, 2011
Contains fulltext : 97170.pdf (Publisher’s version ) (Closed access)A common bacterial strategy to cope with stressful conditions is the activation of alternative sigma factors that control specific regulons enabling targeted responses.
Christof Francke   +9 more
core   +1 more source

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