Results 61 to 70 of about 1,167,503 (297)

Quantitative analysis of primary sigma factor regulons.

, 2015
The total sizes of the primary regulons are listed at the top. Values in the colored cells show the numbers of genes present uniquely within one sigma factor regulon. The intersection values show how many genes were present in two regulons.
Agata Bielecka (269824), Sebastian Bruchmann (703279), Denitsa Eckweiler (185327), Sebastian Schulz (484918), Andreas Dötsch (158223), Juliane Düvel (703280), Klaus Hornischer (14151), Susanne Häussler (158235), Tanja Nicolai (703278), Raimo Franke (87886)   +9 more
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

The Relation between Variances of 3D Density and Its 2D Column Density Revisited

The Astrophysical Journal
We revisit the relation between the variance of three-dimensional (3D) density ( ${\sigma }_{\rho }^{2}$ ) and that of the projected two-dimensional (2D) column density ( ${\sigma }_{{\rm{\Sigma }}}^{2}$ ) in turbulent media, which is of great importance
Heesun Yoon, Jungyeon Cho
doaj   +1 more source

Asymmetric division triggers cell-specific gene expression through coupled capture and stabilization of a phosphatase

eLife, 2015
Formation of a division septum near a randomly chosen pole during sporulation in Bacillus subtilis creates unequal sized daughter cells with dissimilar programs of gene expression.
Niels Bradshaw, Richard Losick
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Anti-Sigma Factors in E. coli: Common Regulatory Mechanisms Controlling Sigma Factors Availability [PDF]

Current Genomics, 2013
In bacteria, transcriptional regulation is a key step in cellular gene expression. All bacteria contain a core RNA polymerase that is catalytically competent but requires an additional σ factor for specific promoter recognition and correct transcriptional initiation. The RNAP core is not able to selectively bind to a given σ factor.
Treviño-Quintanilla, Luis Gerardo, Freyre-González, Julio Augusto, Martínez-Flores, Irma   +2 more
openaire   +2 more sources

Discovery of thiazostatin D/E using UPLC-HR-MS2-based metabolomics and σ-factor engineering of Actinoplanes sp. SE50/110

Frontiers in Bioengineering and Biotechnology
As the natural producer of acarbose, Actinoplanes sp. SE50/110 has high industrial relevance. Like most Actinobacteria, the strain carries several more putative biosynthetic gene clusters (BGCs) to produce further natural products, which are to be ...
Laura Schlüter, Kine Østnes Hansen, Johan Isaksson, Jeanette Hammer Andersen, Espen Holst Hansen, Jörn Kalinowski, Jörn Kalinowski, Yannik Karl-Heinz Schneider   +7 more
doaj   +1 more source

Sequence Determinants Spanning −10 Motif and Spacer Region Implicated in Unique Ehrlichia chaffeensis Sigma 32-Dependent Promoter Activity of dnaK Gene

Frontiers in Microbiology, 2019
Ehrlichia chaffeensis is an obligate intracellular tick-borne bacterium that causes human monocytic ehrlichiosis. Studying Ehrlichia gene regulation is challenge, as this and related rickettsiales lack natural plasmids and mutagenesis experiments are of ...
Huitao Liu, Roman R. Ganta
doaj   +1 more source

Escherichia coli σ70 senses sequence and conformation of the promoter spacer region [PDF]

, 2010
In bacteria, promoter identification by RNA polymerase is mediated by a dissociable p factor. The housekeeping σ70 factor of Escherichia coli recognizes two well characterized DNA sequence elements, known as the ‘-10’ and ‘-35’ hexamers.
Shivani S. Singh, Singh, Shivani, Athanasios Typas, Grainger, David, David C. Grainger, Hengge, R, Typas, Athanasios, Hengge, Regine, Singh, Shivani S., Grainger, David C., Regine Hengge, Typas, A   +11 more
core   +1 more source

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

FEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber, Niki Karavasili, Matthias Kunz, Zemfira Gizatullina, Timur Gainutdinov, Stefan Vielhaber, Wolfram S. Kunz, Frank N. Gellerich   +7 more
wiley   +1 more source