Results 71 to 80 of about 258,387 (282)

The role of SRP9/SRP14 in regulating Alu RNA

open access: yesRNA Biology
SRP9/SRP14 is a protein heterodimer that plays a critical role in the signal recognition particle through its interaction with the scaffolding signal recognition particle RNA (7SL).
Daniel Gussakovsky   +3 more
doaj   +1 more source

Import of honeybee prepromelittin into the endoplasmic reticulum [PDF]

open access: yes, 1987
Honeybee prepromelittin is correctly processed and imported by dog pancreas microsomes. Insertion of prepromelittin into microsomal membranes, as assayed by signal sequence removal, does not depend on signal recognition particle (SRP) and docking protein.
Müller, Günter, Zimmermann, Richard
core   +2 more sources

Reconstruction and Particle Identification for a DIRC System [PDF]

open access: yes, 1998
We study the reconstruction and particle identification (PID) problem for Ring Imaging devices providing a good knowledge of the direction of the Cerenkov photons, as the DIRC system, on which we specialize. We advocate first the use of the stereographic
Aleksan   +14 more
core   +3 more sources

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Immune-mediated Necrotizing Myopathy With Increased Creatine Phosphokinase and Positive Signal Recognition Particle: A Case Report

open access: yesCaspian Journal of Neurological Sciences, 2022
Background: Knowledge about Immune-Mediated Necrotizing Myopathy (IMNM) has received significantly attention in recent years. In this study, we report a rare case of IMNM with increased Creatine Phosphokinase (CPK) and positive Signal Recognition ...
Seyed Mohammad Masoud Hojati   +2 more
doaj  

Feature extraction algorithm of anti-jamming cyclic frequency of electronic communication signal

open access: yesJournal of Intelligent Systems, 2023
Anti-jamming cyclic frequency feature extraction is an important link in identifying communication interference signals, which is of great significance for eliminating electronic communication interference factors and improving the security of electronic
Yang Xuemei
doaj   +1 more source

Depletion of signal recognition particle 72kDa increases radiosensitivity [PDF]

open access: yesCancer Biology & Therapy, 2017
The identification of genetic determinants that underpin tumor radioresistance can help the development of targeted radiosensitizers or aid personalization of radiotherapy treatment. Here we identify signal recognition particle 72kDa (SRP72) as a novel gene involved in radioresistance.
Prevo R.   +5 more
openaire   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Gene Dosage Analysis on the Single-Cell Transcriptomes Linking Cotranslational Protein Targeting to Metastatic Triple-Negative Breast Cancer

open access: yesPharmaceuticals, 2021
Many recent efforts have been put into the association between expression heterogeneity and different cell types and states using single-cell RNA transcriptome analysis.
Yining Liu, Min Zhao
doaj   +1 more source

Sequential activation of human signal recognition particle by the ribosome and signal sequence drives efficient protein targeting [PDF]

open access: yes, 2018
Signal recognition particle (SRP) is a universally conserved targeting machine that mediates the targeted delivery of ∼30% of the proteome. The molecular mechanism by which eukaryotic SRP achieves efficient and selective protein targeting remains elusive.
Chandrasekar, Sowmya   +6 more
core   +2 more sources

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