Results 21 to 30 of about 4,996,865 (347)
Annual Review of Biochemistry, 1998 The transforming growth factor beta (TGF-beta) family of growth factors control the development and homeostasis of most tissues in metazoan organisms. Work over the past few years has led to the elucidation of a TGF-beta signal transduction network. This
J. Massagué
semanticscholar +1 more source
Ethylene Signal Transduction [PDF]
Annals of Botany, 2005 The phytohormone ethylene is a key regulator of plant growth and development. Components of the pathway for ethylene signal transduction were identified by genetic approaches in Arabidopsis and have now been shown to function in agronomically important plants as well.This review focuses on recent advances in our knowledge on ethylene signal ...
Chen, Yi-Feng +2 more
openaire +4 more sources
Salt and drought stress signal transduction in plants.
Annual Review of Plant Biology, 2002 Salt and drought stress signal transduction consists of ionic and osmotic homeostasis signaling pathways, detoxification (i.e., damage control and repair) response pathways, and pathways for growth regulation.
Jian‐Kang Zhu
semanticscholar +1 more source
Robust dimethyl‐based multiplex‐DIA doubles single‐cell proteome depth via a reference channel
Molecular Systems Biology, 2023 Single‐cell proteomics aims to characterize biological function and heterogeneity at the level of proteins in an unbiased manner. It is currently limited in proteomic depth, throughput, and robustness, which we address here by a streamlined multiplexed ...
Marvin Thielert +16 more
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PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancer
Molecular Cancer, 2023 The PI3K/AKT/mTOR (PAM) signaling pathway is a highly conserved signal transduction network in eukaryotic cells that promotes cell survival, cell growth, and cell cycle progression.
Antonino Glaviano +26 more
semanticscholar +1 more source
Frontiers in Nutrition, 2022 The sunflower (Helianthus annuus L.) calathide is gradually used as an alternative treatment for hyperuricemia; nevertheless, evidence regarding its main components and therapeutic capacity for urate nephropathy is lacking.
Huining Dai +8 more
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Enzyme localization can drastically affect signal amplification in signal transduction pathways [PDF]
, 2005 Push-pull networks are ubiquitous in signal transduction pathways in both prokaryotic and eukaryotic cells. They allow cells to strongly amplify signals via the mechanism of zero-order ultrasensitivity.
van Albada, Siebe B. +1 more
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Multi-omics analysis revealed the role of CCT2 in the induction of autophagy in Alzheimer’s disease
Frontiers in Genetics, 2023 Chaperonin containing TCP1 subunit 2 (CCT2) is essential in various neurodegenerative diseases, albeit its role in the pathogenesis of Alzheimer’s disease (AD) remains elusive. This study aimed to evaluate the role of CCT2 in Alzheimer’s disease.
Xueting Ma +6 more
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Subsection signal transduction [PDF]
, 1996 Interactions between human platelets and human umbilical vein endothelial cells (HUVEC) were studied by monitoring changes in cytosolic [Ca2+]i in both cell types. Confluent monolayers of Fura-2-loaded HUVEC, grown on gelatin-coated coverslips, responded
Heemskerk, Johan W.M. +3 more
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Extensive quantitative remodeling of the proteome between normal colon tissue and adenocarcinoma
Molecular Systems Biology, 2012 We report a proteomic analysis of microdissected material from formalin‐fixed and paraffin‐embedded colorectal cancer, quantifying >7500 proteins between patient matched normal mucosa, primary carcinoma, and nodal metastases.
Jacek R Wiśniewski +5 more
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