Results 21 to 30 of about 1,119,972 (297)
Robust dimethyl‐based multiplex‐DIA doubles single‐cell proteome depth via a reference channel
Molecular Systems Biology, 2023 Single‐cell proteomics aims to characterize biological function and heterogeneity at the level of proteins in an unbiased manner. It is currently limited in proteomic depth, throughput, and robustness, which we address here by a streamlined multiplexed ...
Marvin Thielert +16 more
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Signal transduction gRABs attention [PDF]
, 2006 Rab proteins are small GTPases involved in the regulation of vesicular membrane traffic. Research done in the past years has demonstrated that some of these proteins are under the control of signal transduction pathways.
Bucci, Cecilia, Chiariello, Mario
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Frontiers in Nutrition, 2022 The sunflower (Helianthus annuus L.) calathide is gradually used as an alternative treatment for hyperuricemia; nevertheless, evidence regarding its main components and therapeutic capacity for urate nephropathy is lacking.
Huining Dai +8 more
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Watching the hands of the Arabidopsis biological clock [PDF]
, 2001 Oligonucleotide and cDNA microarrays have been used to analyse the mRNA levels of 8,000 genes in Arabidopsis thaliana throughout the day/night cycle. Genes involved in signal transduction and in various metabolic pathways were found to be coordinately ...
Davis, Seth J. +1 more
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Disease Models & Mechanisms, 2019 The unfolded protein response (UPR) involves extensive proteome remodeling in many cellular compartments. To date, a comprehensive analysis of the UPR has not been possible because of technological limitations.
Daniel N. Itzhak +5 more
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Multi-omics analysis revealed the role of CCT2 in the induction of autophagy in Alzheimer’s disease
Frontiers in Genetics, 2023 Chaperonin containing TCP1 subunit 2 (CCT2) is essential in various neurodegenerative diseases, albeit its role in the pathogenesis of Alzheimer’s disease (AD) remains elusive. This study aimed to evaluate the role of CCT2 in Alzheimer’s disease.
Xueting Ma +6 more
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Self-organization of signal transduction
, 2013 We propose a model of parameter learning for signal transduction, where the objective function is defined by signal transmission efficiency. We apply this to learn kinetic rates as a form of evolutionary learning, and look for parameters which satisfy ...
Scheler, Gabriele
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Firing and signal transduction associated with an intrinsic oscillation in neuronal systems [PDF]
, 1998 We study the nonlinear firing and signal transduction of a neuron subject to both a constant stimulus and a weak periodic signal, each of which is too small to, separately, fire spikes for the neuron.
Wang, W, Wang, Y, Wang, ZD
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Finite-State Channel Models for Signal Transduction in Neural Systems
, 2016 Information theory provides powerful tools for understanding communication systems. This analysis can be applied to intercellular signal transduction, which is a means of chemical communication among cells and microbes.
Eckford, Andrew W. +2 more
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Nature Communications, 2018 How tumor cells control metastatic niche formation is not fully understood. Here, the authors show in a lung metastatic niche, high-metastatic hepatocellular carcinoma cells secrete exosomal miR-1247-3p that leads to activation of β1-integrin-NF ...
Tian Fang +15 more
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