Results 21 to 30 of about 1,096,363 (351)

The Active Components of Sunflower (Helianthus annuus L.) Calathide and the Effects on Urate Nephropathy Based on COX-2/PGE2 Signaling Pathway and the Urate Transporter URAT1, ABCG2, and GLUT9

open access: yesFrontiers in Nutrition, 2022
The sunflower (Helianthus annuus L.) calathide is gradually used as an alternative treatment for hyperuricemia; nevertheless, evidence regarding its main components and therapeutic capacity for urate nephropathy is lacking.
Huining Dai   +8 more
doaj   +1 more source

Modeling Cell-to-Cell Communication Networks Using Response-Time Distributions. [PDF]

open access: yes, 2018
Cell-to-cell communication networks have critical roles in coordinating diverse organismal processes, such as tissue development or immune cell response. However, compared with intracellular signal transduction networks, the function and engineering
Altschuler, Steven J   +2 more
core   +2 more sources

Multi-omics analysis revealed the role of CCT2 in the induction of autophagy in Alzheimer’s disease

open access: yesFrontiers in Genetics, 2023
Chaperonin containing TCP1 subunit 2 (CCT2) is essential in various neurodegenerative diseases, albeit its role in the pathogenesis of Alzheimer’s disease (AD) remains elusive. This study aimed to evaluate the role of CCT2 in Alzheimer’s disease.
Xueting Ma   +6 more
doaj   +1 more source

Signal transduction gRABs attention [PDF]

open access: yes, 2006
Rab proteins are small GTPases involved in the regulation of vesicular membrane traffic. Research done in the past years has demonstrated that some of these proteins are under the control of signal transduction pathways.
Bucci, Cecilia, Chiariello, Mario
core   +1 more source

Signal transduction therapy.

open access: yesFolia Pharmacologica Japonica, 1995
Signal transduction is essential for life. In living cells, several signal transduction pathways interact with each other to form complicated signal network. Second messengers, such as Ca2+, cAMP and cGMP, play fundamental roles in the cellular responses via binding to their target proteins. Recent advances in signal transduction research enables us to
A Ichikawa, H Hidaka
openaire   +5 more sources

Watching the hands of the Arabidopsis biological clock [PDF]

open access: yes, 2001
Oligonucleotide and cDNA microarrays have been used to analyse the mRNA levels of 8,000 genes in Arabidopsis thaliana throughout the day/night cycle. Genes involved in signal transduction and in various metabolic pathways were found to be coordinately ...
Davis, Seth J.   +1 more
core   +2 more sources

SILAC-based quantitative proteomics using mass spectrometry quantifies endoplasmic reticulum stress in whole HeLa cells

open access: yesDisease Models & Mechanisms, 2019
The unfolded protein response (UPR) involves extensive proteome remodeling in many cellular compartments. To date, a comprehensive analysis of the UPR has not been possible because of technological limitations.
Daniel N. Itzhak   +5 more
doaj   +1 more source

Response to exercise‐induced blood pressure elevation is blunted in wrist‐cuff automated oscillometric measurement in healthy young college students

open access: yesPhysiological Reports, 2020
Background A wrist‐cuff automated oscillometric device is portable and useful for self‐monitoring of blood pressure (BP) at home and outdoors when an upper arm device is not available.
Tatsuya Sato   +6 more
doaj   +1 more source

Firing and signal transduction associated with an intrinsic oscillation in neuronal systems [PDF]

open access: yes, 1998
We study the nonlinear firing and signal transduction of a neuron subject to both a constant stimulus and a weak periodic signal, each of which is too small to, separately, fire spikes for the neuron.
Wang, W, Wang, Y, Wang, ZD
core   +1 more source

Mitochondrial signal transduction

open access: yesCell Metabolism, 2022
The analogy of mitochondria as powerhouses has expired. Mitochondria are living, dynamic, maternally inherited, energy-transforming, biosynthetic, and signaling organelles that actively transduce biological information. We argue that mitochondria are the processor of the cell, and together with the nucleus and other organelles they constitute the ...
Picard, Martin, Shirihai, Orian S.
openaire   +2 more sources

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