Results 11 to 20 of about 9,547,943 (379)
The JAK/STAT signaling pathway: from bench to clinic
Signal Transduction and Targeted Therapy, 2021 The Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling pathway was discovered more than a quarter-century ago. As a fulcrum of many vital cellular processes, the JAK/STAT pathway constitutes a rapid membrane-to-nucleus ...
Xiaoying Hu +4 more
semanticscholar +1 more source
PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancer
Molecular Cancer, 2023 The PI3K/AKT/mTOR (PAM) signaling pathway is a highly conserved signal transduction network in eukaryotic cells that promotes cell survival, cell growth, and cell cycle progression.
Antonino Glaviano +26 more
semanticscholar +1 more source
Inflammation and tumor progression: signaling pathways and targeted intervention
Signal Transduction and Targeted Therapy, 2021 Cancer development and its response to therapy are regulated by inflammation, which either promotes or suppresses tumor progression, potentially displaying opposing effects on therapeutic outcomes.
Huakan Zhao +6 more
semanticscholar +1 more source
TMG Journal for Media History, 2001 A selection of (media) historic articles from film journals and articles on media in historic cultural journals.
van Beusekom, Ansje, Kester, Bernadette
openaire +54 more sources
SSRN Electronic Journal, 2017 Abstract We study competitive equilibria in a signalling economy with heterogeneously informed buyers. In terms of the classic Spence (1973, The Quarterly Journal of Economics, 87, 355—374) model of job market signalling, firms have access to direct but imperfect information about worker types, in addition to observing their education ...
Kurlat, Pablo, Scheuer, Florian
openaire +4 more sources
The Leading Edge, 2012 Signals are letters to the editor submitted by readers of The Leading Edge.
Malini, Madhavan +2 more
openaire +4 more sources
NF-κB signaling in inflammation
Signal Transduction and Targeted Therapy, 2017 The transcription factor NF-κB regulates multiple aspects of innate and adaptive immune functions and serves as a pivotal mediator of inflammatory responses.
Ting Liu +3 more
semanticscholar +1 more source
Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness
Scientific Reports, 2017 Signaling through the Ror2 receptor tyrosine kinase promotes invadopodia formation for tumor invasion. Here, we identify intraflagellar transport 20 (IFT20) as a new target of this signaling in tumors that lack primary cilia, and find that IFT20 mediates
M. Nishita +11 more
semanticscholar +1 more source
TMG Journal for Media History, 1999 A selection of (media) historic articles from film journals and articles on media in historic cultural journals.
Kester, Bernadette, Smulders, Eric
openaire +8 more sources
Signaling with costly acquisition of signals [PDF]
Journal of Economic Behavior & Organization, 2018 In this paper we investigate the consequences of introducing a cost to observe the signal in an otherwise standard signaling game. Beyond identifying equilibria, which we contrast with those of a standard signaling game, we study their robustness to two important classes of refinements: acting through restrictions on out-of-equilibrium beliefs and ...
Bilancini, Ennio, Boncinelli, Leonardo
openaire +6 more sources