Results 61 to 70 of about 403,629 (240)
Frontiers in PharmacologyIntroductionOpioid drugs are potent analgesics that mimic the endogenous opioid peptides, endorphins and enkephalins, by activating the µ-opioid receptor.
Sarah Warren Gooding +12 more
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Flagellar dynamics reveal fluctuations and kinetic limit in the Escherichia coli chemotaxis network
Scientific Reports, 2023 The Escherichia coli chemotaxis network, by which bacteria modulate their random run/tumble swimming pattern to navigate their environment, must cope with unavoidable number fluctuations (“noise”) in its molecular constituents like other signaling ...
Roshni Bano +3 more
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Neural Signals for the Detection of Unintentional Race Bias [PDF]
Psychological Science, 2004 We examined the hypothesis that unintentional race-biased responses may occur despite the activation of neural systems that detect the need for control. Participants completed a sequential priming task that induced race-biased responses on certain trials while electroencephalography was recorded. The error-related negativity (ERN) wave, a component of
David M, Amodio +5 more
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MoleculesKappa opioid receptor (KOR) agonists have well-established antinociceptive effects. However, many KOR agonists have negative side effects, which limit their therapeutic potential.
Ross van de Wetering +8 more
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Asymmetric thymocyte death underlies the CD4:CD8 T-cell ratio in the adaptive immune system [PDF]
, 2013 It has long been recognized that the T-cell compartment has more CD4 helper than CD8 cytotoxic T cells, and this is most evident looking at T-cell development in the thymus.
Bains, Iren +3 more
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iScience, 2022 Summary: The EphA2 receptor tyrosine kinase activates signaling pathways with different, and sometimes opposite, effects in cancer and other pathologies.
Maricel Gomez-Soler +7 more
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Utility measurement: Signal, noise, and bias
Organizational Behavior and Human Decision Processes, 1992 Abstract Recent research has documented various violations of procedural invariance, ranging from preference reversals to discrepancies among theoretically equivalent utility encoding methods. This paper explores multiple causes for such discrepancies, focusing on the effects and possible interactions of (1) random noise, (2) insufficient adjustment ...
Paul J.H Schoemaker, John C Hershey
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MASS-DEPENDENT BARYON ACOUSTIC OSCILLATION SIGNAL AND HALO BIAS [PDF]
The Astrophysical Journal, 2013 We characterize the baryon acoustic oscillations (BAO) feature in halo two-point statistics using N-body simulations. We find that nonlinear damping of the BAO signal is less severe for halos in the mass range we investigate than for dark matter. The amount of damping depends weakly on the halo mass. The correlation functions show a mass-dependent drop
Wang, Qiao, Zhan, Hu
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Kir3 channel signaling complexes: Focus on opioid receptor signaling
Frontiers in Cellular Neuroscience, 2014 Opioids are among the most effective drugs to treat severe pain. They produce their analgesic actions by specifically activating opioid receptors located along the pain perception pathway where they inhibit the flow of nociceptive information.
Karim eNagi, Graciela ePineyro
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Blood flow-induced Notch activation and endothelial migration enable vascular remodeling in zebrafish embryos. [PDF]
, 2018 Arteries and veins are formed independently by different types of endothelial cells (ECs). In vascular remodeling, arteries and veins become connected and some arteries become veins. It is unclear how ECs in transforming vessels change their type and how
Ablooglu, Ararat J +6 more
core +3 more sources