Results 91 to 100 of about 1,690,858 (268)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Chengshi guidao jiaotong yanjiu[Objective] The signaling system for Xi’an Metro Line 2 Phase Ⅰ project (hereinafter referred to as Line 2) utilizes an imported system, while Phase Ⅱ adopts a domestically developed system.
SUN Hui, REN Yaping, LIANG Bo
doaj +1 more source
Cross-regulation in a three-component cell envelope stress signaling system of <i>Brucella</i>. [PDF]
mBio, 2023 Chen X +3 more
europepmc +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Overhaul and Renovation Plan for Signaling System of Shanghai Rail Transit Line 6
Chengshi guidao jiaotong yanjiu[Objective] After years of operation, Shanghai Rail Transit Line 6 signaling system faces equipment aging and frequent failures. To enhance this system reliability, adaptability, and operational efficiency, it is imperative to develop an overhaul plan ...
WU Min, XU Yan, ZHANG Yu
doaj +1 more source
Spatiotemporal regulation of the BarA/UvrY two-component signaling system. [PDF]
J Biol Chem, 2023 Contreras FU +5 more
europepmc +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Kongzhi Yu Xinxi JishuThe preliminary signaling design for urban rail transit systems often encounters challenges related to unreasonable reliability allocation due to incomplete statistical data on failures. To address this issue, this paper presents a reliability allocation
XU Zhengjie
doaj
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Exploration to Automatic Turn-back of CBTC Signaling
机车电传动, 2014 To implement metro vehicle automatic turn-back without human, automatic turn-back schemes based on CBTC system was studied, and automatic turn-back method from one end with ATC was introduced.
XU Juan +3 more
doaj