Results 91 to 100 of about 1,678,713 (260)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Status and Development of Train Tracking Technology for CBTC Signaling System
Kongzhi Yu Xinxi Jishu, 2019 The existing train tracking technology research of communication based train control (CBTC) signaling system is generally limited to details or particular characteristics.
WANG Lili, LI Lei
doaj
Analysis and Solution Schemes for Interference on Metro Signaling System Axle Counting Equipment
Chengshi guidao jiaotong yanjiu[Objective] During the system commissioning, train debugging and trial operation on Chengdu Metro Line 18, the axle counting equipment exhibits AIO (abnormal interference and occupation) due to various disturbances in different scenarios, significantly ...
Rongbing YANG +3 more
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Time Synchronization Scheme for Train FAO Signaling System
Chengshi guidao jiaotong yanjiu[Objective] Time synchronization is the foundation for ensuring the coordinated linkage of sub-systems within the signaling system, which directly affects the punctuality and operational safety of trains, serving as the basis for achieving train FAO ...
Qiguang HUANG, Yu LIANG
doaj +1 more source
Research on Data Platform of Urban Rail Signaling Intelligent Operation and Maintenance System
Kongzhi Yu Xinxi Jishu, 2021 Aiming at the problem of massive data processing in the construction and application of urban rail signaling intelligent operation and maintenance system, this paper studies a data platform of urban rail signaling intelligent operation and maintenance ...
DENG Yongqi, YANG Jiang, YANG Yibin
doaj
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Research on Signaling System of City (Suburban) Railway Cross-line Operation to Intercity Railway
Chengshi guidao jiaotong yanjiuObjective City (suburban) railways are a weak link in the four-network integrated development of rail transit system in China. There is currently no unified understanding regarding their functional positioning and passenger flow demands.
Xiangfei DENG
doaj +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source