Results 71 to 80 of about 1,678,713 (260)

Strategy for Selecting Signaling System Types for Suburban Railways

open access: yesChengshi guidao jiaotong yanjiu
ObjectiveThe mainstream signaling systems for suburban railways are CTCS2+ATO (Chinese train control system level 2 + automatic train operation) and CBTC (communication-based train control).
Lin CHEN, Rui SONG, Ning DANG, Yifan QIU
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Signaling System in Middle-low-speed Maglev Train

open access: yes机车电传动, 2011
This paper mainly introduced the signaling system, working principle and function of middle-low-speed maglev train. The signaling system design used an integrated idea, which had set automatic block, computer interlocking control and train control and ...
李文波
doaj  

Cybersecurity Situational Awareness System Applicable for Urban Rail Transit CBTC System

open access: yesChengshi guidao jiaotong yanjiu
Objective Urban rail transit CBTC (communication-based train control) systems face complex and diverse cybersecurity challenges. Existing cybersecurity tools feature high false alarm rates and poor adaptation to CBTC systems, lacking in-depth analysis of
LIU Dongdong   +5 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

DEVELOPMENT OF STATE ARBITRATION BODIES IN KEMEROVO REGION IN THE 1950S – EARLY 1960S

open access: yesВестник Кемеровского государственного университета, 2014
The paper analyses the development of Kemerovo region state arbitration bodies in the 1950s and the early 1960s. The author exploits archive materials and investigates into the measures taken to improve the work of these bodies.
D. V. Voronin
doaj  

Trackside Resource Management Scheme Based on Integration of TACS and CBTC Systems

open access: yesChengshi guidao jiaotong yanjiu
[Objective] Traditional signaling systems manage trackside resources using routing-based methods and calculate movement authority accordingly. In contrast, the TACS (train autonomous circumnavigation system) manages resources from the perspective of ...
ZHANG Chong, CHEN Shaowen
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

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