Results 81 to 90 of about 1,678,713 (260)
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Objective To improve the real-time, accuracy, and efficiency of information services, and enhance the operational service efficiency and quality of Shanghai rail transit, it is essential to optimize the interface content between the audio video unified ...
DU Qijun
doaj +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
[Objective]Compared to the CBTC (communication-based train control) system, CTCS2+ATO (Chinese train control system level 2 + automatic train operation) system requires longer usable track lengths due to its built-in protection zones, leading to ...
SONG Rui
doaj +1 more source
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Train In-station Coupling and Decoupling Scheme for Shanghai Metro Line 16
Objective Shanghai Metro Line 16 adopts a flexible marshalling operation mode, but it takes a long time for the train to complete the coupling and decoupling process, leading to great difficulty in train operation organization.
CUI Yong
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Key Points in Line Splitting for Hangzhou Metro Line 1 Linping Branch
ObjectiveThe splitting and renovation construction of metro operating lines is a highly complex task that involves multiple professional disciplines and challenges related to compatibility between new and existing systems. Such projects are characterized
Zhiming SUN
doaj +1 more source
[Objective] As urban rail transit lines in many major cities across China have entered the system upgrade stage, it is crucial to ensure the safety, reliability, and efficiency of transition switching engineering during the upgrade process, which will ...
YE Fuzhi +5 more
doaj +1 more source

