Results 81 to 90 of about 1,690,858 (268)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Signaling System in Middle-low-speed Maglev Train

open access: yes机车电传动, 2011
This paper mainly introduced the signaling system, working principle and function of middle-low-speed maglev train. The signaling system design used an integrated idea, which had set automatic block, computer interlocking control and train control and ...
李文波
doaj  

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Analysis and Solution Schemes for Interference on Metro Signaling System Axle Counting Equipment

open access: yesChengshi guidao jiaotong yanjiu
[Objective] During the system commissioning, train debugging and trial operation on Chengdu Metro Line 18, the axle counting equipment exhibits AIO (abnormal interference and occupation) due to various disturbances in different scenarios, significantly ...
Rongbing YANG   +3 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Time Synchronization Scheme for Train FAO Signaling System

open access: yesChengshi guidao jiaotong yanjiu
[Objective] Time synchronization is the foundation for ensuring the coordinated linkage of sub-systems within the signaling system, which directly affects the punctuality and operational safety of trains, serving as the basis for achieving train FAO ...
Qiguang HUANG, Yu LIANG
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

DEVELOPMENT OF STATE ARBITRATION BODIES IN KEMEROVO REGION IN THE 1950S – EARLY 1960S

open access: yesВестник Кемеровского государственного университета, 2014
The paper analyses the development of Kemerovo region state arbitration bodies in the 1950s and the early 1960s. The author exploits archive materials and investigates into the measures taken to improve the work of these bodies.
D. V. Voronin
doaj  

Research on Signaling System of City (Suburban) Railway Cross-line Operation to Intercity Railway

open access: yesChengshi guidao jiaotong yanjiu
Objective City (suburban) railways are a weak link in the four-network integrated development of rail transit system in China. There is currently no unified understanding regarding their functional positioning and passenger flow demands.
Xiangfei DENG
doaj   +1 more source

Involvement of the Notch signaling system in alveolar bone resorption. [PDF]

open access: yesJpn Dent Sci Rev, 2023
Jakovljevic A   +6 more
europepmc   +1 more source

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