Results 111 to 120 of about 31,177,116 (343)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Optimization of Interface Content between Shanghai Rail Transit Audio Video Unified Information Service System and Signaling System

open access: yesChengshi guidao jiaotong yanjiu
Objective To improve the real-time, accuracy, and efficiency of information services, and enhance the operational service efficiency and quality of Shanghai rail transit, it is essential to optimize the interface content between the audio video unified ...
DU Qijun
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Solution to Shorten Track Usable Length at City Railway Turnout Stations by Using Continuation Routes

open access: yesChengshi guidao jiaotong yanjiu
[Objective]Compared to the CBTC (communication-based train control) system, CTCS2+ATO (Chinese train control system level 2 + automatic train operation) system requires longer usable track lengths due to its built-in protection zones, leading to ...
SONG Rui
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Train In-station Coupling and Decoupling Scheme for Shanghai Metro Line 16

open access: yesChengshi guidao jiaotong yanjiu
Objective Shanghai Metro Line 16 adopts a flexible marshalling operation mode, but it takes a long time for the train to complete the coupling and decoupling process, leading to great difficulty in train operation organization.
CUI Yong
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Key Points in Line Splitting for Hangzhou Metro Line 1 Linping Branch

open access: yesChengshi guidao jiaotong yanjiu
ObjectiveThe splitting and renovation construction of metro operating lines is a highly complex task that involves multiple professional disciplines and challenges related to compatibility between new and existing systems. Such projects are characterized
Zhiming SUN
doaj   +1 more source

Technical Analysis of Transition Switching Engineering in Urban Rail Transit Signaling System Upgrades

open access: yesChengshi guidao jiaotong yanjiu
[Objective] As urban rail transit lines in many major cities across China have entered the system upgrade stage, it is crucial to ensure the safety, reliability, and efficiency of transition switching engineering during the upgrade process, which will ...
YE Fuzhi   +5 more
doaj   +1 more source

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