Results 101 to 110 of about 2,656,427 (351)

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Key Points in Line Splitting for Hangzhou Metro Line 1 Linping Branch

open access: yesChengshi guidao jiaotong yanjiu
ObjectiveThe splitting and renovation construction of metro operating lines is a highly complex task that involves multiple professional disciplines and challenges related to compatibility between new and existing systems. Such projects are characterized
Zhiming SUN
doaj   +1 more source

Train In-station Coupling and Decoupling Scheme for Shanghai Metro Line 16

open access: yesChengshi guidao jiaotong yanjiu
Objective Shanghai Metro Line 16 adopts a flexible marshalling operation mode, but it takes a long time for the train to complete the coupling and decoupling process, leading to great difficulty in train operation organization.
CUI Yong
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Technical Analysis of Transition Switching Engineering in Urban Rail Transit Signaling System Upgrades

open access: yesChengshi guidao jiaotong yanjiu
[Objective] As urban rail transit lines in many major cities across China have entered the system upgrade stage, it is crucial to ensure the safety, reliability, and efficiency of transition switching engineering during the upgrade process, which will ...
YE Fuzhi   +5 more
doaj   +1 more source

Сигнальні системи та проблеми мислення особистості норми і патології (Signal system and problems of thinking of personality in health and disease) [PDF]

open access: yes, 2010
У статті розглядаються історичні складові та перспективи міждисциплінарних досліджень сигнальних систем, мови і мислення особистості у єдиному функціональному комплексі.
Романюк , В. Л. (V. Romaniuk)
core  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Status and Development of Train Tracking Technology for CBTC Signaling System

open access: yesKongzhi Yu Xinxi Jishu, 2019
The existing train tracking technology research of communication based train control (CBTC) signaling system is generally limited to details or particular characteristics.
WANG Lili, LI Lei
doaj  

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