Spatiotemporal regulation of the BarA/UvrY two-component signaling system. [PDF]
J Biol Chem, 2023 Contreras FU +5 more
europepmc +1 more source
Probing signal amplification by reversible exchange using an NMR flow system
, 2014 Ryan E. Mewis +10 more
openalex +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Safety Evaluation of Urban Rail Transit Signal System Based on HAZOP and ALARP Principles
机车电传动, 2018 Safety requirements of subway signaling system in operating stage were analysed, the potential risks of evaluating and controlling the signal system based on HAZOP (Hazard and Operability Analysis) and ALARP (as Low as Reasonably Practicable) affecting ...
MO Zhigang, LUO Hanbin
doaj
Urban Rail Transit Signaling System Status Assessment Method Based on Analytic Hierarchy Process
Chengshi guidao jiaotong yanjiu[Objective] Shanghai rail transit signaling system faces challenges including large scale, complex model variations, and inconsistent operational lifespans.
WU Min, ZHANG Yu, CAO Yuan
doaj +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Research on Protection Section Setting of Urban Rail Transit Signaling System
Kongzhi Yu Xinxi Jishu, 2020 In urban rail transit, signaling system needs to set up overlap reasonably so as to meet the requirements of high speed route terminal train approaching, precise train stopping, and also to ensure driving safety.
ZHANG Datao
doaj
Single-Cell Measurements and Modeling and Computation of Decision-Making Errors in a Molecular Signaling System with Two Output Molecules. [PDF]
Biology (Basel), 2023 Emadi A +3 more
europepmc +1 more source
Systems analysis of latent HIV reversal reveals altered stress kinase signaling and increased cell death in infected T cells [PDF]
, 2017 Linda Fong +2 more
openalex +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source