Results 121 to 130 of about 2,656,427 (351)

Involvement of the Notch signaling system in alveolar bone resorption. [PDF]

Jpn Dent Sci Rev, 2023
Jakovljevic A, Nikolic N, Paternò Holtzman L, Tournier P, Gaudin A, Cordaro L, Milinkovic I.   +6 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Overhaul and Renovation Plan for Signaling System of Shanghai Rail Transit Line 6

Chengshi guidao jiaotong yanjiu
[Objective] After years of operation, Shanghai Rail Transit Line 6 signaling system faces equipment aging and frequent failures. To enhance this system reliability, adaptability, and operational efficiency, it is imperative to develop an overhaul plan ...
WU Min, XU Yan, ZHANG Yu
doaj   +1 more source

Cross-regulation in a three-component cell envelope stress signaling system of <i>Brucella</i>. [PDF]

mBio, 2023
Chen X, Alakavuklar MA, Fiebig A, Crosson S.   +3 more
europepmc   +1 more source

A Somatic Cell Genetic System for Dissecting Hemopoietic Cytokine Signal Transduction [PDF]

, 2002
Rachael T. Richardson, Robyn Starr, Leecia J.L. Angus, Douglas J. Hilton   +3 more
openalex   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Two-Series-Connected Two-Level PWM Inverter With Three-Level Input Feature: Offset Voltage Injection and Continuous/Discontinuous Modulation Strategies

IEEE Access
This paper presents a two-series-connected two-level PWM inverter with a three-level input feature for high input-voltage applications. Unlike conventional multilevel converters such as diode-clamped inverters, the proposed topology eliminates clamping ...
Min-Sup Song
doaj   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Exploration to Automatic Turn-back of CBTC Signaling

机车电传动, 2014
To implement metro vehicle automatic turn-back without human, automatic turn-back schemes based on CBTC system was studied, and automatic turn-back method from one end with ATC was introduced.
XU Juan, ZHENG LIhua, LI Hui, TANG Guoping   +3 more
doaj  

Analysis and Implementation of the MNRV DPWM Methods Applied to Single-Phase Diode-Clamped Four-Level PWM Inverter

IEEE Access
This paper introduces the multi-neighboring reference vector discontinuous pulse-width modulation (MNRV DPWM) with offset voltage injection methodology tailored for single-phase diode-clamped four-level PWM inverters.
Min-Sup Song
doaj   +1 more source