Results 141 to 150 of about 31,177,116 (343)
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
IEEE AccessThis paper introduces the multi-neighboring reference vector discontinuous pulse-width modulation (MNRV DPWM) with offset voltage injection methodology tailored for single-phase diode-clamped four-level PWM inverters.
Min-Sup Song
doaj +1 more source
Spatiotemporal regulation of the BarA/UvrY two-component signaling system. [PDF]
J Biol Chem, 2023 Contreras FU +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
New-generation Signaling System Construction Scheme Based on Cloud Architecture
Chengshi guidao jiaotong yanjiu[Objective] With the theme of promoting urban rail transit information, developing intelligent system, and building 'smart urban rail' for a highly integrated urban rail transit cloud platform is the direction of technological development in the new era.
Minjie LIU, Gang WU
doaj +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Safety Evaluation of Urban Rail Transit Signal System Based on HAZOP and ALARP Principles
机车电传动, 2018 Safety requirements of subway signaling system in operating stage were analysed, the potential risks of evaluating and controlling the signal system based on HAZOP (Hazard and Operability Analysis) and ALARP (as Low as Reasonably Practicable) affecting ...
MO Zhigang, LUO Hanbin
doaj
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Urban Rail Transit Signaling System Status Assessment Method Based on Analytic Hierarchy Process
Chengshi guidao jiaotong yanjiu[Objective] Shanghai rail transit signaling system faces challenges including large scale, complex model variations, and inconsistent operational lifespans.
WU Min, ZHANG Yu, CAO Yuan
doaj +1 more source