Results 191 to 200 of about 2,656,427 (351)

Discovery and functional characterization of a bombesin-type neuropeptide signaling system in an invertebrate. [PDF]

Proc Natl Acad Sci U S A
Huang W, Zhong X, Zampronio CG, Bottrill AR, Jones KGE, Tinoco AB, Guo L, Egertová M, Mirabeau O, Elphick MR.   +9 more
europepmc   +1 more source

High-Level Expression of Cell-Surface Signaling System Hxu Enhances Pseudomonas aeruginosa Bloodstream Infection. [PDF]

Infect Immun, 2022
Yang F, Zhou Y, Chen P, Cai Z, Yue Z, Jin Y, Cheng Z, Wu W, Yang L, Ha UH, Bai F.   +10 more
europepmc   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

The Interplay Among HIV, LINE-1, and the Interferon Signaling System. [PDF]

Front Immunol, 2021
Zhao X, Zhao Y, Du J, Gao P, Zhao K.
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Ovarian tachykinin signaling system induces the growth of secondary follicles during the gonadotropin-independent process. [PDF]

J Biol Chem
Kawada T, Aoyama M, Matsubara S, Osugi T, Sakai T, Kirimoto S, Nakaoka S, Sugiura Y, Yasuda K, Satake H.   +9 more
europepmc   +1 more source

Roles of the FGF-FGFR Signaling System in Cancer Development and Inflammation. [PDF]

Cells, 2021
Wiedlocha A, Haugsten EM, Zakrzewska M.
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

The NmpRSTU multi-component signaling system of Myxococcus xanthus regulates expression of an oxygen utilization regulon. [PDF]

J Bacteriol
McAllister CT, Ronk AM, Stenzel MJ, Kirby JR, Bretl DJ.   +4 more
europepmc   +1 more source

Molecular model of a sensor of two-component signaling system. [PDF]

Sci Rep, 2021
Ryzhykau YL, Orekhov PS, Rulev MI, Rulev MI, Vlasov AV, Melnikov IA, Volkov DA, Nikolaev MY, Zabelskii DV, Murugova TN, Chupin VV, Rogachev AV, Gruzinov AY, Svergun DI, Brennich ME, Gushchin IY, Soler-Lopez M, Bothe A, Büldt G, Leonard G, Engelhard M, Kuklin AI, Gordeliy VI.   +22 more
europepmc   +1 more source