Results 21 to 30 of about 19,728,514 (315)
Modularity in signaling systems [PDF]
Modularity is a property by which the behavior of a system does not change upon interconnection. It is crucial for understanding the behavior of a complex system from the behavior of the composing subsystems. Whether modularity holds in biology is an intriguing and largely debated question.
openaire +4 more sources
Nitrosothiols in the immune system: Signaling and protection [PDF]
Antioxidants and Redox Signaling 18.3 (2013): 288-308Significance: In the immune system, nitric oxide (NO) has been mainly associated with antibacterial defenses exerted through oxidative, nitrosative, and nitrative stress and signal transduction through
García-Ortiz, Almudena +11 more
core +1 more source
Dissecting the impact of Frizzled receptors in Wnt/beta-catenin signaling of human mesenchymal stem cells [PDF]
Wnt/beta-catenin signaling is of fundamental importance in the regulation of self-renewal, migration/invasion, and differentiation of human mesenchymal stem cells (hMSCs).
Ruiz-Heinrich, Lourdes +18 more
core +1 more source
A Systems Approach for Decoding Mitochondrial Retrograde Signaling Pathways
Mitochondrial dysfunctions activate retrograde signaling from mitochondria to the nucleus. To identify transcription factors and their associated pathways that underlie mitochondrial retrograde signaling, we performed gene expression profiling of the ...
Sehyun Chae +7 more
core +1 more source
Any living cell parasitizing a host organism is immersed into a molecular environment of unfathomable complex- ity. For the advancement of its life cycle in such “hostile” a territory, the cell has to carefully sense its environment, “see” the ongoing ...
Jorge Navarro, Pedro C. Marijuán
doaj +1 more source
Compression System for the Phonocardiographic Signal [PDF]
An FPGA-based approach is proposed for implementing a compression system developed specifically for the signal of phonocardiogram. The compression method offers better rate and distorsion than standard audio compression techniques. Both the algorithm and the details on the solutions adopted for its implementation are presented in this paper.
Legaz Cano, A. +4 more
openaire +3 more sources
Purinergic signalling in systemic sclerosis
Abstract SSc is a chronic autoimmune rheumatic disease that involves numerous organs and presents major management challenges. The histopathologic hallmarks of SSc include vasculopathy, fibrosis and autoimmune phenomena involving both innate and adaptive immune systems.
Höppner, Jakob +6 more
openaire +2 more sources
Three-Phase Diode-Clamped Four-Level PWM Inverter With Offset Voltage Injection
In this paper, a three-phase diode-clamped four-level PWM inverter with offset voltage injection is proposed. The proposed inverter is based on multi-neighboring reference vector (discontinuous) pulse-width modulation (MNRV (D)PWM), where multiple ...
Min-Sup Song, Jaewon Kim, Hwan-Hee Cho
doaj +1 more source
A HOSPITAL SIGNAL SYSTEM. [PDF]
In October, 1904, I devised, for the Hospital of the Good Samaritan, a signal system for calling nurses to patients, which has the following advantages: Noiseless. There being no bells, the call is absolutely silent. Monitor board. This is in the office of the superintendent of nurses and enables this officer or her representatives to observe each ...
openaire +2 more sources

