Results 41 to 50 of about 1,678,713 (260)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

How a Bacillus “Sees” the World: Information Needs and Signaling Resources of Mycobacterium Tuberculosis

open access: yestripleC: Communication, Capitalism & Critique, 2011
Any living cell parasitizing a host organism is immersed into a molecular environment of unfathomable complex- ity. For the advancement of its life cycle in such “hostile” a territory, the cell has to carefully sense its environment, “see” the ongoing ...
Jorge Navarro, Pedro C. Marijuán
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Signals and Systems

open access: yes
The book titled Signals and Systems provides a detailed introduction to the fundamentals of signals and systems, focusing on their classification, characteristics, and key operations. It begins with the definition of signals and systems, covering various types such as continuous-time and discrete-time signals. The text explores the different categories
Fatos Tunay Yarman Vural, Emre Akbas
  +7 more sources

Comparison between TACS and CBTC System Degradation Impacts in Urban Rail Transit

open access: yesChengshi guidao jiaotong yanjiu
[Objective] To meet increasing urban rail transit capacity demands, traditional CBTC (communication-based train control) signaling systems-with ground-based interlocking as core architecture-are evolving toward TACS (train autonomous circumnavigation ...
WANG Chen   +4 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Analysis of the Interface between Urban Rail Transit Signaling System and Platform Screen Door System

open access: yesChengshi guidao jiaotong yanjiu
Objective The control of PSD (platform screen doors) by signaling system is crucial for ensuring urban rail transit stable operation. The interface between the signaling system and the PSD system is equally important for the stable and efficient control ...
ZHANG Sikai
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

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