Pulsatile Hormonal Signaling to Extracellular Signal-Regulated Kinase: Exploring System Sensitivity to Gonadotropin-Releasing Hormone Pulse Frequency and Width [PDF]
, 2014 Gonadotropin-releasing hormone (GnRH) is secreted in brief pulses that stimulate synthesis and secretion of pituitary gonadotropin hormones and thereby mediate control of reproduction.
Armstrong +41 more
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Cold Signaling via the Two-Component Signaling System [PDF]
Molecular Plant, 2013 Two-component signal transduction is commonly used as a stimulus–response coupling mechanism to allow organisms such as eubacteria, archea, and a few eukaryotes to sense and respond to changes in many different environmental conditions (Stock et al., 2000).
Kim, Jungmook, Jeon, Jin
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Subverting sterols: rerouting an oxysterol-signaling pathway to promote tumor growth. [PDF]
, 2013 Oxysterols are oxidized derivatives of cholesterol that are generated enzymatically or through autoxidation. Initially identified as important lipid signaling molecules in the context of atherosclerosis and inflammation, accumulated evidence indicates ...
Bensinger, Steven J, York, Autumn G
core +1 more source
Information transfer in signaling pathways : a study using coupled simulated and experimental data [PDF]
, 2008 Background: The topology of signaling cascades has been studied in quite some detail. However, how information is processed exactly is still relatively unknown.
Pahle, Jürgen +3 more
core +5 more sources
Three-Phase Diode-Clamped Four-Level PWM Inverter With Offset Voltage Injection
IEEE AccessIn this paper, a three-phase diode-clamped four-level PWM inverter with offset voltage injection is proposed. The proposed inverter is based on multi-neighboring reference vector (discontinuous) pulse-width modulation (MNRV (D)PWM), where multiple ...
Min-Sup Song, Jaewon Kim, Hwan-Hee Cho
doaj +1 more source
Effects of RANKL-Targeted Therapy in Immunity and Cancer. [PDF]
, 2014 The role of the receptor activator of nuclear factor-κB ligand (RANKL)/RANK system is well characterized within bone, where RANKL/RANK signaling mediates osteoclastogenesis and bone resorption.
Cheng, Michael L, Fong, Lawrence
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Modularity in signaling systems [PDF]
Physical Biology, 2012 Modularity is a property by which the behavior of a system does not change upon interconnection. It is crucial for understanding the behavior of a complex system from the behavior of the composing subsystems. Whether modularity holds in biology is an intriguing and largely debated question.
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Reproductive Biology and Endocrinology, 2015 BackgroundExpression of kisspeptin (protein) and Kiss1r (mRNA) was recently documented in the mouse uterus on D4 of pregnancy (the day of embryo implantation) suggesting that the uterine-based kisspeptin (KP)/kisspeptin receptor (KISS1R) signaling system
M. Fayazi +5 more
semanticscholar +1 more source
Bactericidal antibiotic treatment induces damaging inflammation via TLR9 sensing of bacterial DNA
Nature CommunicationsThe immunologic consequences of using bactericidal versus bacteriostatic antibiotic treatments are unclear. We observed a bacteriostatic (growth halting) treatment was more protective than a bactericidal (bacteria killing) treatment in a murine ...
Julia L. Gross +8 more
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One-Leg Half-Bridge Diode-Clamped Four-Level PWM Inverter Based on MNRV PWM
IEEE AccessThis paper introduces a one-leg half-bridge (HB) diode-clamped four-level PWM inverter incorporating the multi-neighboring reference vector pulse-width modulation (MNRV PWM) methodology.
Min-Sup Song, Hyungchul Kim
doaj +1 more source