Results 31 to 40 of about 19,728,514 (315)

Split histidine kinases enable ultrasensitivity and bistability in two-component signaling networks [PDF]

open access: yes, 2012
Bacteria sense and respond to their environment through signaling cascades generally referred to as two-component signaling networks. These networks comprise histidine kinases and their cognate response regulators.
Steven L Porter   +16 more
core   +2 more sources

The Signals And Systems Concept Inventory [PDF]

open access: yes2002 Annual Conference Proceedings, 2005
The signal processing community needs quantitative standardized tools to assess student learning in order to improve teaching methods and satisfy accreditation requirements. The Signals and Systems Concept Inventory (SSCI) is a 25-question multiple-choice exam designed to measure students' understanding of fundamental concepts taught in standard ...
Kathleen E. Wage   +3 more
openaire   +2 more sources

Tumor Angiocrine Signaling: Novel Targeting Opportunity in Cancer

open access: yes, 2023
The vascular endothelium supplies nutrients and oxygen to different body organs and supports the progression of diseases such as cancer through angiogenesis.
Janine Terra Erler   +3 more
core   +1 more source

Bactericidal antibiotic treatment induces damaging inflammation via TLR9 sensing of bacterial DNA

open access: yesNature Communications
The immunologic consequences of using bactericidal versus bacteriostatic antibiotic treatments are unclear. We observed a bacteriostatic (growth halting) treatment was more protective than a bactericidal (bacteria killing) treatment in a murine ...
Julia L. Gross   +8 more
doaj   +1 more source

One-Leg Half-Bridge Diode-Clamped Four-Level PWM Inverter Based on MNRV PWM

open access: yesIEEE Access
This paper introduces a one-leg half-bridge (HB) diode-clamped four-level PWM inverter incorporating the multi-neighboring reference vector pulse-width modulation (MNRV PWM) methodology.
Min-Sup Song, Hyungchul Kim
doaj   +1 more source

The Ubiquitin System and Jasmonate Signaling [PDF]

open access: yesPlants, 2016
The ubiquitin (Ub) system is involved in most, if not all, biological processes in eukaryotes. The major specificity determinants of this system are the E3 ligases, which bind and ubiquitinate specific sets of proteins and are thereby responsible for target recruitment to the proteasome or other cellular processing machineries.
Astrid Nagels Durand   +2 more
openaire   +3 more sources

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider   +15 more
wiley   +1 more source

CLE peptide signaling during plant development [PDF]

open access: yes, 2009
Peptide signaling in plants is a rapid developing area of research which focuses on so called peptide hormones. These signaling molecules are utilized for inter-cellular communication in different developmental processes, beside the usage of the more ...
Fiers, M.A.   +3 more
core   +1 more source

Systems theory of Smad signalling [PDF]

open access: yesIEE Proceedings - Systems Biology, 2006
Transforming Growth Factor-beta (TGF-beta) signalling is an important regulator of cellular growth and differentiation. The principal intracellular mediators of TGF-beta signalling are the Smad proteins, which upon TGF-beta stimulation accumulate in the nucleus and regulate transcription of target genes.
Clarke, D. C., Betterton, M. D., Liu, X.
openaire   +3 more sources

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz   +12 more
wiley   +1 more source

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