Results 71 to 80 of about 1,649,371 (295)

Key Points in Line Splitting for Hangzhou Metro Line 1 Linping Branch

open access: yesChengshi guidao jiaotong yanjiu
ObjectiveThe splitting and renovation construction of metro operating lines is a highly complex task that involves multiple professional disciplines and challenges related to compatibility between new and existing systems. Such projects are characterized
Zhiming SUN
doaj   +1 more source

Train In-station Coupling and Decoupling Scheme for Shanghai Metro Line 16

open access: yesChengshi guidao jiaotong yanjiu
Objective Shanghai Metro Line 16 adopts a flexible marshalling operation mode, but it takes a long time for the train to complete the coupling and decoupling process, leading to great difficulty in train operation organization.
CUI Yong
doaj   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

Technical Analysis of Transition Switching Engineering in Urban Rail Transit Signaling System Upgrades

open access: yesChengshi guidao jiaotong yanjiu
[Objective] As urban rail transit lines in many major cities across China have entered the system upgrade stage, it is crucial to ensure the safety, reliability, and efficiency of transition switching engineering during the upgrade process, which will ...
YE Fuzhi   +5 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Status and Development of Train Tracking Technology for CBTC Signaling System

open access: yesKongzhi Yu Xinxi Jishu, 2019
The existing train tracking technology research of communication based train control (CBTC) signaling system is generally limited to details or particular characteristics.
WANG Lili, LI Lei
doaj  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Analysis and Solution Schemes for Interference on Metro Signaling System Axle Counting Equipment

open access: yesChengshi guidao jiaotong yanjiu
[Objective] During the system commissioning, train debugging and trial operation on Chengdu Metro Line 18, the axle counting equipment exhibits AIO (abnormal interference and occupation) due to various disturbances in different scenarios, significantly ...
Rongbing YANG   +3 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Home - About - Disclaimer - Privacy