Results 71 to 80 of about 2,656,427 (351)

Diffusive Molecular Communications with Reactive Signaling

open access: yes, 2017
This paper focuses on molecular communication (MC) systems where the signaling molecules may participate in a reversible bimolecular reaction in the channel.
Farsad, Nariman   +3 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Research on Shanghai Rail Transit Signaling System Evolution Scheme

open access: yesChengshi guidao jiaotong yanjiu
Objective With the rapid development of urban rail transit, the operational volume of trains has significantly increased. The existing CBTC (communication-based train control) system can no longer meet the signaling system needs of high-density ...
WANG Lizhou
doaj   +1 more source

Identification of control targets in Boolean molecular network models via computational algebra [PDF]

open access: yes, 2016
Motivation: Many problems in biomedicine and other areas of the life sciences can be characterized as control problems, with the goal of finding strategies to change a disease or otherwise undesirable state of a biological system into another, more ...
Aguilar, Boris   +3 more
core   +5 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

QoS Strategies for Wired Communication Networks in Urban Rail Transit Signaling System

open access: yesChengshi guidao jiaotong yanjiu
Objective With the increase in data traffic and diversification of data types in urban rail transit signaling systems, higher demands are placed on reliability, real-time performance, and security.
XU Yongshun
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Signaling System Fully Redundant On-board Architecture Suitable for TACS

open access: yesChengshi guidao jiaotong yanjiu
Objective The signaling system of Shanghai Rail Transit Line 3 and Line 4 can no longer meet the requirements of high-density and high-reliability networked operation, necessitating an upgrade to TACS (train autonomous circumambulate system).
NI Zhihao
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Signaling System Transformation Scheme for Adding Memorized Train Location Function to Stabling Track of Shanghai Rail Transit Existing Lines

open access: yesChengshi guidao jiaotong yanjiu
[Objective] When Shanghai Rail Transit existing lines using CBTC (communication-based train control) signaling system adopts the mainline night time storage mode, after powering up on the following day, the driver starts the train in restricted manual ...
ZHAO Hongbin
doaj   +1 more source

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