Results 81 to 90 of about 1,649,371 (295)

Time Synchronization Scheme for Train FAO Signaling System

open access: yesChengshi guidao jiaotong yanjiu
[Objective] Time synchronization is the foundation for ensuring the coordinated linkage of sub-systems within the signaling system, which directly affects the punctuality and operational safety of trains, serving as the basis for achieving train FAO ...
Qiguang HUANG, Yu LIANG
doaj   +1 more source

Research on Data Platform of Urban Rail Signaling Intelligent Operation and Maintenance System

open access: yesKongzhi Yu Xinxi Jishu, 2021
Aiming at the problem of massive data processing in the construction and application of urban rail signaling intelligent operation and maintenance system, this paper studies a data platform of urban rail signaling intelligent operation and maintenance ...
DENG Yongqi, YANG Jiang, YANG Yibin
doaj  

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Research on Signaling System of City (Suburban) Railway Cross-line Operation to Intercity Railway

open access: yesChengshi guidao jiaotong yanjiu
Objective City (suburban) railways are a weak link in the four-network integrated development of rail transit system in China. There is currently no unified understanding regarding their functional positioning and passenger flow demands.
Xiangfei DENG
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Compatibility Implementation Plan for Xi’an Metro Line 2 Phase Ⅰ and Phase Ⅱ Project Signaling Systems

open access: yesChengshi guidao jiaotong yanjiu
[Objective] The signaling system for Xi’an Metro Line 2 Phase Ⅰ project (hereinafter referred to as Line 2) utilizes an imported system, while Phase Ⅱ adopts a domestically developed system.
SUN Hui, REN Yaping, LIANG Bo
doaj   +1 more source

Involvement of the Notch signaling system in alveolar bone resorption. [PDF]

open access: yesJpn Dent Sci Rev, 2023
Jakovljevic A   +6 more
europepmc   +1 more source

INTELLECTUAL FORECASTING OF SPEECH SIGNAL IN THE SYSTEM OF CONFIDENTIAL COMMUNICATION ON THE NETWORK WITH DEDICATED CHANNELS

open access: diamond, 2021
V.I. Korniienko   +4 more
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

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