Results 11 to 20 of about 546,808 (280)

Identifying Signatures of Selection in Genetic Time Series [PDF]

Genetics, 2013
Both genetic drift and natural selection cause the frequencies of alleles in a population to vary over time. Discriminating between these two evolutionary forces, based on a time series of samples from a population, remains an outstanding problem with ...
Feder, Alison, Kryazhimskiy, Sergey, Plotkin, Joshua B.   +2 more
core   +3 more sources

Identification of selection signatures in livestock species

Genetics and Molecular Biology, 2014
The identification of regions that have undergone selection is one of the principal goals of theoretical and applied evolutionary genetics. Such studies can also provide information about the evolutionary processes involved in shaping genomes, as well as
João José de Simoni Gouveia, Marcos Vinicius Gualberto Barbosa da Silva, Samuel Rezende Paiva, Sônia Maria Pinheiro de Oliveira   +3 more
doaj   +4 more sources

Signatures of selection with cultural interference. [PDF]

Proc Natl Acad Sci U S A
Human evolution is intricately linked with culture, which permeates almost all facets of human life from health and reproduction, to the environments in which we live. Nevertheless, our understanding of the ways in which stably transmitted, evolutionarily relevant human cultural traits might interact with the human genome is incomplete, and methods to ...
Fogarty L, Otto SP.
europepmc   +5 more sources

Signatures of selection in recently domesticated macadamia. [PDF]

Nat Commun, 2022
AbstractMacadamia is a high value nut crop that is recently domesticated, ideal for testing the effect of artificial selection. Here, we sequence the genome of Hawaiian cultivar ‘Kau’ and assemble into 794 Mb in 14 pseudo-chromosomes with 37,728 genes. Genome analysis reveals a whole-genome duplication event, occurred 46.8 million years ago.
Lin J, Zhang W, Zhang X, Ma X, Zhang S, Chen S, Wang Y, Jia H, Liao Z, Lin J, Zhu M, Xu X, Cai M, Zeng H, Wan J, Yang W, Matsumoto T, Hardner C, Nock CJ, Ming R.   +19 more
europepmc   +6 more sources

Detecting signatures of selection on gene expression [PDF]

Nature Ecology & Evolution, 2022
A substantial amount of phenotypic diversity results from changes in gene expression levels and patterns. Understanding how the transcriptome evolves is therefore a key priority in identifying mechanisms of adaptive change. However, in contrast to powerful models of sequence evolution, we lack a consensus model of gene expression evolution. Furthermore,
Peter D. Price, Daniela H. Palmer Droguett, Jessica A. Taylor, Dong Won Kim, Elsie S. Place, Thea F. Rogers, Judith E. Mank, Christopher R. Cooney, Alison E. Wright   +8 more
openaire   +3 more sources

Complex signatures of natural selection at GYPA [PDF]

Human Genetics, 2018
The human MN blood group antigens are isoforms of glycophorin A (GPA) encoded by the gene, GYPA, and are the most abundant erythrocyte sialoglycoproteins. The distribution of MN antigens has been widely studied in human populations yet the evolutionary and/or demographic factors affecting population variation remain elusive.
Abigail W. Bigham, Kevin Magnaye, Diane M. Dunn, Robert B. Weiss, Michael Bamshad   +4 more
openaire   +2 more sources

Deciphering signatures of natural selection via deep learning [PDF]

Briefings in Bioinformatics, 2021
Abstract Identifying genomic regions influenced by natural selection provides fundamental insights into the genetic basis of local adaptation. However, it remains challenging to detect loci under complex spatially varying selection. We propose a deep learning-based framework, DeepGenomeScan, which can detect signatures of spatially ...
Xinghu Qin, Charleston W. K. Chiang, Oscar E. Gaggiotti   +2 more
openaire   +4 more sources

Signature of balancing selection in Arabidopsis [PDF]

Proceedings of the National Academy of Sciences, 2002
Natural selection and genetic linkage cause DNA segments to have genealogical histories resembling those of the selected sites. When a polymorphism maintained by selection is old, it will have an island of enhanced sequence variability surrounding it, which represents a detectable “signature of selection.” We investigate the ...
Dacheng, Tian, Hitoshi, Araki, Eli, Stahl, Joy, Bergelson, Martin, Kreitman   +4 more
openaire   +2 more sources

Whole-genome scan of population differentiation in Zel and Lori-Bakhtiari sheep breeds [PDF]

مجله بیوتکنولوژی کشاورزی, 2010
Selection for increasing of frequency in new mutations that are advantageous only in a subset of populations leaves some signatures in the genome. Detecting these genomic regions is one of the most important areas of research in animal genetics since ...
Mohammad hossein Moradi, Ardeshir Nejati, Mohammad Moradi, ken Dadz, jan mak ivan   +4 more
doaj   +1 more source

The genetic mechanisms underlying the convergent evolution of pollination syndromes in the Neotropical radiation of Costus L.

Frontiers in Plant Science, 2022
Selection together with variation in floral traits can act to mold floral form, often driven by a plant’s predominant or most effective pollinators. To investigate the evolution of traits associated with pollination, we developed a phylogenetic framework
Eugenio Valderrama, Jacob B. Landis, Jacob B. Landis, Dave Skinner, Paul J. M. Maas, Hiltje Maas-van de Kramer, Thiago André, Nikolaus Grunder, Chodon Sass, Maria Pinilla-Vargas, Clarice J. Guan, Heather R. Phillips, Ana Maria Rocha de Almeida, Chelsea D. Specht   +13 more
doaj   +1 more source