Results 61 to 70 of about 42,464 (273)

Cadmium-induced adrenal cortical autophagy in rats: possible modulation by sildenafil

open access: yesFolia Morphologica, 2020
BACKGROUND: The link between autophagy, inflammatory bowel disease, ischaemic injury and cancer had been established. Reasonable evidence is available for cadmium to be related to certain cancers.
R. A. Imam   +2 more
doaj   +1 more source

Preoperative subcutaneous sildenafil injection increases random flap survival in rats [PDF]

open access: yesActa Cirúrgica Brasileira, 2018
Purpose: To investigate the effect of subcutaneous sildenafil on random flap survival. Methods: Fourteen Wistar rats, which were divided in to two groups, were used for this experimental study.
Merdan Serin   +6 more
doaj   +2 more sources

Interventional therapies for chronic heart failure: An overview of recent developments

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1081-1094, April 2025.
Abstract Heart failure (HF), the final manifestation of most cardiovascular diseases, has become a major global health concern, affecting millions of individuals. Despite basic drug treatments, patients present with high morbidity and mortality rates. However, recent advancements in interventional therapy have shown promising results in improving the ...
Bingchen Guo   +7 more
wiley   +1 more source

Current practices in the use of sildenafil for pulmonary arterial hypertension in Brazilian hospitals

open access: yesBMC Research Notes, 2009
Background Sildenafil is a cyclic guanosine monophosphate-specific phosphodiesterase-5 inhibitor used for treating pulmonary hypertension. Although the use of sildenafil in patients under 18 years old is off-label, this inhibitor has been widely ...
Cabral Lucio M   +2 more
doaj   +1 more source

Development and characterization of polymer-coated liposomes for vaginal delivery of sildenafil citrate

open access: yesDrug Delivery, 2017
Vaginal administration of sildenafil citrate has shown recently to develop efficiently the uterine lining with subsequent successful embryo implantation following in vitro fertilization.
H. Refai   +2 more
semanticscholar   +1 more source

Cilostazol in patients with heart failure and preserved ejection fraction—The CLIP‐HFpEF trial

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1437-1446, April 2025.
• Cilostazol is an oral PDE‐3 inhibitor that may have advantageous effects in heart failure with preserved ejection fraction (HFpEF). • Cilostazol significantly improved short‐term heart failure‐related health status scores (KCCQ‐12) and NT‐proBNP levels when compared to placebo.
Norman Aiad   +9 more
wiley   +1 more source

Sildenafil promotes osteogenic differentiation of human mesenchymal stem cells and inhibits bone loss by affecting the TGF-β signaling pathway

open access: yesStem Cell Research & Therapy
Background Osteoporosis, a common bone disorder, is primarily managed pharmacologically. However, existing medications are associated with non-trivial side-effects.
Menglong Hu   +9 more
doaj   +1 more source

Use of sildenafil citrate in cases of intrauterine growth restriction (IUGR); a prospective trial

open access: yesTaiwanese Journal of Obstetrics & Gynecology, 2018
Objective: Intrauterine growth restriction (IUGR) is one of the most serious complications of pregnancy. Up to date, there is no evidence of achieving antenatal treatment of IUGR with abnormal placentation.
Mohammed Maged   +3 more
doaj   +1 more source

Direct comparison of tadalafil with sildenafil for the treatment of erectile dysfunction: a systematic review and meta-analysis

open access: yesInternational Urology and Nephrology, 2017
AimsErectile dysfunction (ED) is a major care problem worldwide. Tadalafil and sildenafil are the two most common phosphodiesterase 5 inhibitors used to treat ED.
Bin-Bin Gong   +7 more
semanticscholar   +1 more source

The situational Samaritan: How group reputation threat shapes reparatory behavior

open access: yesJournal of Consumer Psychology, EarlyView.
Abstract Consumers often act to correct the wrongdoings of people close to them, such as family members or friends. The current research demonstrates that consumers may also engage in a variety of reparatory behaviors—from a simple apology to gift‐giving and tipping—to counter the misdeeds of in‐group strangers when their behavior threatens the ...
Julia Von Schuckmann   +3 more
wiley   +1 more source

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