Results 91 to 100 of about 10,448 (268)

Ameliorative Role of β‐Caryophyllene on Antioxidant Biomarkers in a Paroxetine‐Induced Model of Male Sexual Dysfunction

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 136, Issue 3, March 2025.
ABSTRACT Male sexual dysfunction, characterised by reduced libido, ejaculatory issues and erectile dysfunction, often results from oxidative stress and enzymatic imbalance, notably involving phosphodiesterase type 5 (PDE5) and nitric oxide synthase (NOS).
Elijah Oluwatosin Olopade   +5 more
wiley   +1 more source

Evaluating handheld spectroscopic techniques for identifying counterfeit branded and generic medicines worldwide [PDF]

open access: yes, 2016
Counterfeit medicines represent a global public health problem which accounts for 10% of the world market including 50% in some countries. Medicine counterfeiting can occur to any class of medicines, any type of formulation and can be encountered ...
Assi, Sulaf
core  

Part 2: Drug Interactions Involving Cannabis Products in Persons Aged 18 and Over: A Summary of Published Case Reports and Analysis of the FDA Adverse Event Reporting System

open access: yesPharmacology Research &Perspectives, Volume 13, Issue 1, February 2025.
ABSTRACT The increasing utilization of cannabis products combined with lack of data regarding potential cannabis–prescription drug interactions is concerning. This study aimed to review published case reports and FDA Adverse Event Reporting System (FAERS) spontaneous reports to assess cannabis–drug interactions in persons aged 18 and over. A literature
Maryann R. Chapin   +7 more
wiley   +1 more source

Protective effect of Sildenafil on contralateral epididymal sperm concentration and motility following unilateral blunt testicular trauma in pre-pubertal male mice [PDF]

open access: yes, 2015
Background and aims: Blunt testicular trauma adversely affects fertility in later periods. The purpose of the present study was to examine the effect of sildenafil on contralateral epididymal sperm count and motility following unilateral blunt testicular
Behfar, Mehdi.   +3 more
core  

Sildenafil as a therapeutic option for digital ischemic ulceration: case report. [PDF]

open access: yes, 2015
We report the case of a 37-year-old woman who developed critical upper limb ischemia caused by a cervical rib. Because the malformation was initially undiagnosed, a vascular bypass was performed, and failure occurred.
Applegate, L.A.   +5 more
core   +1 more source

Is sildenafil citrate affect endometrial receptivity? an immunohistochemical study

open access: yesGynecological Endocrinology, 2010
The authors aimed to investigate the effect of sildenafil citrate (Sc) on expressions of β(3) integrin and vascular endothelial growth factor (VEGF), which is taking part in endometrium receptivity in implantation window period in controlled ovarian hyperstimulation (COH) performed rats.
Biyiksiz, Pelin Costur   +2 more
openaire   +5 more sources

Development and stability assessment of liquid paediatric formulations containing sildenafil citrate

open access: yesBrazilian Journal of Pharmaceutical Sciences, 2013
The purpose of this study is to develop and improve oral liquids formulations of sildenafil citrate for paediatric use. Four different formulations were developed, which are as follows: two aqueous solutions of sildenafil citrate (2.5 mg/mL), with or ...
Fátima Roque   +3 more
doaj   +1 more source

Validation and Stability Indicating RP-HPLC Method for the Determination of Sildenafil Citrate in Pharmaceutical Formulations and Human Plasma

open access: yesE-Journal of Chemistry, 2008
A simple, selective, accurate reverse phase-high performance liquid chromatographic (RP-HPLC) method was developed and validated for the analysis of sildenafil citrate in pharmaceutical formulations. Chromatographic separation achieved isocratically on a
B. Prasanna Kumar Reddy   +1 more
doaj   +1 more source

The effect of phosphodiesterase-5 inhibitors on cerebral blood flow in humans: A systematic review. [PDF]

open access: yes, 2018
Agents that augment cerebral blood flow (CBF) could be potential treatments for vascular cognitive impairment. Phosphodiesterase-5 inhibitors are vasodilating drugs established in the treatment of erectile dysfunction (ED) and pulmonary hypertension.
Barrick, TR   +6 more
core   +1 more source

Finger roots (Uvaria chemea) and African greenheart (Cylicodiscus gabunensis): Alternative potent therapy to sildenafil in erectile dysfunction

open access: yesPhytomedicine Plus
Background and aim: Erectile dysfunction (ED) is a prevalent condition affecting men worldwide, characterized by the inability to achieve or maintain an erection sufficient for sexual intercourse. Traditional herbal remedies, rooted in cultural practices,
Etukudo Okon Jimmy   +5 more
doaj   +1 more source

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