Results 91 to 100 of about 10,725 (262)
Progress and Application of Multifunctional Hydrogel in Radioactive Skin Injury
Advanced Materials Interfaces, Volume 12, Issue 11, June 9, 2025.This review examines healing challenges in radiation‐wound injuries, where ionizing radiation impairs immune and tissue repair processes. Hydrogels, with their biocompatibility, antimicrobial properties, and drug delivery capabilities, present a transformative solution. It compares hydrogel efficacy in radiation‐induced versus common wounds, highlights
Xinyue Cui +5 more
wiley +1 more source
Acta Physiologica, Volume 241, Issue 5, May 2025.Abstract Aim H+ facilitates metabolic blood flow regulation while negatively impacting cardiac contractility. Cardiovascular consequences of conjugate bases accumulating alongside H+ remain unclear. Here, we evaluate the cardiovascular effects of nine prominent carboxylates—particularly lactate, 3‐hydroxybutyrate, and butyrate—linked to metabolic and ...
Casper Homilius +5 more
wiley +1 more source
Journal of Veterinary Internal Medicine, Volume 39, Issue 3, May/June 2025.ABSTRACT Background Myxomatous mitral valve disease (MMVD) can cause pulmonary hypertension (PH). Mitral valve repair (MVR) has been described as a surgical treatment option for MMVD, but the benefit of MVR when PH is present is unknown. Hypothesis/Objectives To investigate the change in echocardiographic variables and long‐term outcomes of dogs with ...
Tomohiko Yoshida +2 more
wiley +1 more source
Long-term cardioprotection with phosphodiesterase-5 inhibition against ischemia-reperfusion injury: Role of nitric oxide. [PDF]
, 2005 Recent studies have shown that the potent phosphodiesterase-5 (PDE-5) inhibitor, sildenafil citrate, induces a powerful cardioprotective effect against ischemia-reperfusion (I/R) injury in rabbit and mouse hearts.
Daoud, Vladimir Paul
core +1 more source
A survey of Top 200 Drugs—Inconsistent Practice of Drug Strength Expression for Drugs Containing Salt Forms [PDF]
, 2012 Many ionizable drugs are developed and marketed as salt forms. However, there are no clear US regulatory guidelines on drug strength labeling for salts. The strengths of some drugs are expressed as salts and some as free acids/bases.
Prohotsky, Daniel, Zhao, Fang
core +2 more sources
Development and stability assessment of liquid paediatric formulations containing sildenafil citrate
Brazilian Journal of Pharmaceutical Sciences, 2013 The purpose of this study is to develop and improve oral liquids formulations of sildenafil citrate for paediatric use. Four different formulations were developed, which are as follows: two aqueous solutions of sildenafil citrate (2.5 mg/mL), with or ...
Fátima Roque +3 more
doaj +1 more source
Sildenafil as a therapeutic option for digital ischemic ulceration: case report. [PDF]
, 2015 We report the case of a 37-year-old woman who developed critical upper limb ischemia caused by a cervical rib. Because the malformation was initially undiagnosed, a vascular bypass was performed, and failure occurred.
Applegate, L.A. +5 more
core +1 more source
E-Journal of Chemistry, 2008 A simple, selective, accurate reverse phase-high performance liquid chromatographic (RP-HPLC) method was developed and validated for the analysis of sildenafil citrate in pharmaceutical formulations. Chromatographic separation achieved isocratically on a
B. Prasanna Kumar Reddy +1 more
doaj +1 more source
The solubility of soldenafil citrate in propylene glycol-polyethylene glycol systems [PDF]
, 2018 Исследованы закономерности растворения силденафила цитрата в смесях вода-полиэтиленгликоль с молекулярными массами 200, 400 и 600, полиэтиленгликоль-400 - 1,2-пропиленгликоль, а также подкисленные до рН 4 системы полиэтиленгликоль-400 - 1,2 ...
Кондратов, Сергей Алексеевич +4 more
core +1 more source
Protective effect of Sildenafil on contralateral epididymal sperm concentration and motility following unilateral blunt testicular trauma in pre-pubertal male mice [PDF]
, 2015 Background and aims: Blunt testicular trauma adversely affects fertility in later periods. The purpose of the present study was to examine the effect of sildenafil on contralateral epididymal sperm count and motility following unilateral blunt testicular
Behfar, Mehdi. +3 more
core