Results 11 to 20 of about 3,731 (172)
Laboratory Animal Research, 2023 Background The clinical use of sildenafil citrate (Viagra), a drug used to treat erectile dysfunction, is limited because of its many side effects on tissues.
Ibrahim M. Ibrahim Laila +2 more
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Urethral dysfunction due to alloxan-induced diabetes. Urodynamic evaluation and action of sildenafil citrate [PDF]
Acta Cirúrgica Brasileira, 2014 PURPOSE: To evaluate the effect of diabetes mellitus and of sildenafil citrate on female urethral function.METHODS: Twenty nine female rats were divided into four groups: G1 - (n=9), normal rats; G2 - (n=6), normal rats treated with sildenafil citrate ...
Ana Beatriz Gomes de Souza Pegorare +5 more
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EFFECT OF LONG-TERM ADMINISTRATION OF SILDENAFIL CITRATE (VIAGRA) ON SOME SPERM CHARACTERISTICS AND TESTIS ARCHITECTURE OF MALE RATS [PDF]
Basrah Journal of Veterinary Research, 2009 Sildenafil citrate (Viagra) is an oral medication used to treat male impotence by the inhibition of phosphodiesterase-5 in the corpus cavernosum and subsequent facilitation of penile erection.
Khalid G. Al-Fartosi
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Sildenafil citrate monohydrate [PDF]
Acta Crystallographica Section E Structure Reports Online, 2005 Sildenafil citrate is well known as Viagra for the treatment of erectile dysfuncion. In the title compound (systematic name: 1-{[3-(6,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl}-4-methylpiperazinium citrate monohydrate), C22H31N6O4S+·C6H7O7−·H2O, the pyrazolopyrimidone ring system and the ...
Yathirajan, H. S. +3 more
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Evaluation of cardiac injury biomarkers in serum following concomitant administration of sildenafil citrate with dextromethorphan and chlorpheniramine in rat [PDF]
Āsīb/shināsī-i Darmāngāhī-i Dāmpizishkī, 2021 Sildenafil citrate is an inhibitor of the enzyme phosphodiesterase 5, dextromethorphan is an antitussive with weak opioid effects, and chlorpheniramine is a first-generation antihistamine.
Rasol Sadeghy +2 more
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Clinical update on sildenafil citrate [PDF]
British Journal of Clinical Pharmacology, 2002 The timing of this edition's supplement containing papers on the pharmacokinetic and pharmacodynamic properties of sildenafil citrate (Viagra®, Pfizer) appears very apt. It comes at a time when sildenafil has been marketed in Europe for approximately 3 years and when there is increasing interest and focus on men's health. Indeed a recent edition of the
Ian H, Osterloh, Alan, Riley
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Effect of sildenafil citrate on the cardiovascular system
Brazilian Journal of Medical and Biological Research, 2005 Sildenafil citrate is a drug commonly used to manage erectile dysfunction. It is designated chemically as 1-[[3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H -pyrazolo[4,3-d]pyrimidin-5-yl)-4 ethoxyphenyl] sulfonyl]-4-methylpiperazine citrate (C22H30N6O4 S ...
K. Shinlapawittayatorn +2 more
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Ups and downs of Viagra: revisiting ototoxicity in the mouse model. [PDF]
PLoS ONE, 2013 Sildenafil citrate (Viagra), a phosphodiesterase 5 inhibitor (PDE5i), is a commonly prescribed drug for erectile dysfunction. Since the introduction of Viagra in 1997, several case reports have linked Viagra to sudden sensorineural hearing loss. However,
Adrian Au +3 more
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Use of sildenafil citrate in cases of intrauterine growth restriction (IUGR); a prospective trial
Taiwanese Journal of Obstetrics & Gynecology, 2018 Objective: Intrauterine growth restriction (IUGR) is one of the most serious complications of pregnancy. Up to date, there is no evidence of achieving antenatal treatment of IUGR with abnormal placentation.
Mohammed Maged +3 more
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Oral bioavailability and pharmacokinetics of sildenafil citrate dry foam tablets in rats
Cogent Medicine, 2018 Sildenafil has low water solubility and oral bioavailability. Dry foam formulations of solid dosage forms of poorly water-soluble drugs may exhibit improved dissolution and bioavailability.
Somchai Sawatdee +7 more
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