Results 41 to 50 of about 9,248 (216)

The solubility of soldenafil citrate in propylene glycol-polyethylene glycol systems [PDF]

, 2018
Исследованы закономерности растворения силденафила цитрата в смесях вода-полиэтиленгликоль с молекулярными массами 200, 400 и 600, полиэтиленгликоль-400 - 1,2-пропиленгликоль, а также подкисленные до рН 4 системы полиэтиленгликоль-400 - 1,2 ...
Кондратов, Сергей Алексеевич, Олейников, Дмитрий Сергеевич, Савяк, Роман Прокопович, Тимко, Владимир Григорьевич, Черный, Александр Александрович   +4 more
core   +1 more source

Analisis Sildenafil Sitrat Pada Jamu Tradisional Kuat Lelaki Merk a Dan B Dengan Metode Kromatografi Cair Kinerja Tinggi [PDF]

, 2010
Recently, addition of chemical into traditional medicine has been a subject of study. One of them is sildenafil citrate. The aim of this study is to analize Sildenafil Citrate in Jamu kuat lelaki Brand A and B with High Performance Liquid ...
Kusuma, A. M. (Anjar), Sarigih, A. T. (Angga), Utami, P. I. (Pri)   +2 more
core  

Nitric oxide regulates skeletal muscle fatigue, fiber type, microtubule organization, and mitochondrial ATP synthesis efficiency through cGMP-dependent mechanisms [PDF]

, 2016
Aim: Skeletal muscle nitric oxide–cyclic guanosine monophosphate (NO-cGMP) pathways are impaired in Duchenne and Becker muscular dystrophy partly because of reduced nNOSμ and soluble guanylate cyclase (GC) activity.
Balke, Jordan E, Brouckaert, Peter, Buys, Emmanuel S, Knowels, Gary, Madorma, Derik, Marcinek, David J, Moon, Younghye, Percival, Justin M, Siegel, Michael P   +8 more
core   +1 more source

Targeting G3BP1 Condensate Topology Promotes Stress Granule Assembly via m6A‐IGF2BP1 for Ischemic Stroke Rescue

Advanced Science, Volume 13, Issue 6, 30 January 2026.
Our research reveals that small‐molecule icariin (ICA) directly binds Ras‐GTPase‐activating protein SH3 domain‐binding protein 1 (G3BP1), inducing conformational change and oligomerization. This interaction confers neuroprotection by recruiting insulin‐like growth factor 2 mRNA‐binding protein 1 (IGF2BP1) and modulating N6‐methyladenosine (m6A ...
Ling Li, Yong‐Dong Guo, Xiao‐Wen Zhang, Zhi‐Yong Du, Yu‐Qi Wang, Zhuo Yang, Qian‐Wei Luo, Fang‐Fang Zhuo, Tian‐Tian Wei, Zheng‐Ping Liu, Bo Han, Wei Yu, Pei‐Pei Zhang, Wei Zhou, Zhi‐Yuan Lu, Peng‐Fei Tu, Chun‐Hong Zheng, Ke‐Wu Zeng   +17 more
wiley   +1 more source

The effects of sildenafil ciltrate on the lateral geniculate body of adult Wistar rats (Rattus norvegicus)- A histological study [PDF]

, 2010
The histological effect of oral administration of sildenafil citrate (Viagra), commonly used as an aphrodisiac and for the treatment of erectile dysfunction on one of the visual relay centres namely the lateral geniculate body (LGB) of adult Wistar rat ...
Eweka, A, Eweka, AO
core   +1 more source

Utilization of Fertility Treatment in Japan During the First Year of Insurance Coverage: Analysis of Real‐World Health Claims Data

Reproductive Medicine and Biology, Volume 25, Issue 1, January/December 2026.
ABSTRACT Purpose In April 2022, fertility treatments, including assisted reproductive technology (ART), became eligible for public health insurance coverage in Japan. This study describes the prevalence and characteristics of infertility diagnoses and fertility treatments during the first year of coverage.
Makoto Okawara, Tomoichiro Kuwazuru, Moe Masunaga, Kenji Fujimoto, Masako Nagata, Takeshi Iwasa, Yoshihisa Fujino   +6 more
wiley   +1 more source

Oxidative stress in pre-eclampsia; have we been looking in the wrong place? [PDF]

, 2017
Pre-eclampsia is a disorder of late pregnancy. It is a major cause of maternal and perinatal morbidity and mortality, accounting for nearly 18% of all maternal deaths worldwide; an estimated 77,000 maternal deaths per year [1].
Kenny, Louise C., McCarthy, Cathal, McCarthy, Fergus P., Williamson, Rachel D.   +3 more
core   +1 more source

Emerging Trends and Research Focus in Erectile Dysfunction Treatment: A 1993–2023 Bibliometric Analysis

Andrologia, Volume 2026, Issue 1, 2026.
Erectile dysfunction (ED) is a common sexual disorder worldwide significantly affects men’s quality of life. However, there remains a lack of comprehensive bibliometric analysis of ED treatment. This study aims to utilize bibliometric methods to assess the research progress in ED treatment and identify the research hot spots and emerging trends in this
Kefan Li, Wenpeng Song, Zhuo Zhou, Xiaohui Tan, Mancheng Xia, Pengchao Gao, Fangzhou Zhao, Honggang Ying, Weidong Song, Zhongcheng Xin, Yiming Yuan, Woong Jin Bae, Ruili Guan, Harleen Khatra   +13 more
wiley   +1 more source

Sexual function after external-beam radiotherapy for prostate cancer: What do we know? [PDF]

, 2006
Quality of life in general and sexual functioning in particular have become very important in cancer patients. Due to modern surgical techniques, improved quality of drugs for chemotherapy and very modern radiation techniques, more patients can be ...
Incrocci, L. (Luca)
core   +4 more sources

Astragaloside IV alleviates hypoxic pulmonary hypertension by inhibiting RELM‐β to reduce PINK1/Parkin‐mediated mitophagy in pulmonary artery smooth muscle cells (PASMCs)

British Journal of Pharmacology, Volume 182, Issue 24, Page 5933-5952, December 2025.
Background and Purpose Hypoxic pulmonary hypertension (HPH) is a chronic disorder marked by irreversible pulmonary vascular remodelling (PVR) and pulmonary artery smooth muscle cell (PASMC) dysfunction. Astragaloside IV (AS‐IV), a natural saponin from Astragalus, shows potential in HPH management. This study explores AS‐IV's protective effect on PVR in
Rongzhen Ding, Haiping Xie, Shuliu Sang, Li Qin, Yinhui Sun, Chao Zhang, Jian Yi, Hui Liu, Jianmin Fan, Guoran Peng, BeiBei Cheng, Lan Song, Aiguo Dai   +12 more
wiley   +1 more source