Clinical update on sildenafil citrate [PDF]
British Journal of Clinical Pharmacology, 2002 The timing of this edition's supplement containing papers on the pharmacokinetic and pharmacodynamic properties of sildenafil citrate (Viagra®, Pfizer) appears very apt. It comes at a time when sildenafil has been marketed in Europe for approximately 3 years and when there is increasing interest and focus on men's health. Indeed a recent edition of the
Ian H, Osterloh, Alan, Riley
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Sildenafil citrate monohydrate [PDF]
Acta Crystallographica Section E Structure Reports Online, 2005 Sildenafil citrate is well known as Viagra for the treatment of erectile dysfuncion. In the title compound (systematic name: 1-{[3-(6,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl}-4-methylpiperazinium citrate monohydrate), C22H31N6O4S+·C6H7O7−·H2O, the pyrazolopyrimidone ring system and the ...
Yathirajan, H. S. +3 more
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Effective of Sildenafil Citrate on Pregnancy Outcome in infertile women undergoing induction of ovulation by Letrzole and Clomiphene Citrate [PDF]
Al-Azhar International Medical Journal, 2022 Background: Endometrium consists of a simple columnar epithelium, forming numerous tubular glands, supported by a thick vascular stromal. Both glands and stromal undergo extensive changes during the menstrual cycle.
Ayman AbdAllah Elashmawy +2 more
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Use of sildenafil citrate in cases of intrauterine growth restriction (IUGR); a prospective trial
Taiwanese Journal of Obstetrics & Gynecology, 2018 Objective: Intrauterine growth restriction (IUGR) is one of the most serious complications of pregnancy. Up to date, there is no evidence of achieving antenatal treatment of IUGR with abnormal placentation.
Mohammed Maged +3 more
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Evaluation of cardiac injury biomarkers in serum following concomitant administration of sildenafil citrate with dextromethorphan and chlorpheniramine in rat [PDF]
Āsīb/shināsī-i Darmāngāhī-i Dāmpizishkī, 2021 Sildenafil citrate is an inhibitor of the enzyme phosphodiesterase 5, dextromethorphan is an antitussive with weak opioid effects, and chlorpheniramine is a first-generation antihistamine.
Rasol Sadeghy +2 more
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Ups and downs of Viagra: revisiting ototoxicity in the mouse model. [PDF]
PLoS ONE, 2013 Sildenafil citrate (Viagra), a phosphodiesterase 5 inhibitor (PDE5i), is a commonly prescribed drug for erectile dysfunction. Since the introduction of Viagra in 1997, several case reports have linked Viagra to sudden sensorineural hearing loss. However,
Adrian Au +3 more
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Oral bioavailability and pharmacokinetics of sildenafil citrate dry foam tablets in rats
Cogent Medicine, 2018 Sildenafil has low water solubility and oral bioavailability. Dry foam formulations of solid dosage forms of poorly water-soluble drugs may exhibit improved dissolution and bioavailability.
Somchai Sawatdee +7 more
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Effect of sildenafil in cavernous arteries of patients with erectile dysfunction
International Brazilian Journal of Urology, 2003 INTRODUCTION: Sildenafil citrate is a type 5 phosphodiesterase inhibitor, which has demonstrated excellent results in the treatment of erectile dysfunction.
Joaquim A Claro +5 more
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Effects and mechanisms of action of sildenafil citrate in human chorionic arteries
Reproductive Biology and Endocrinology, 2009 Objectives Sildenafil citrate, a specific phosphodiesterase-5 inhibitor, is increasingly used for pulmonary hypertension in pregnancy. Sildenafil is also emerging as a potential candidate for the treatment of intra-uterine growth retardation and for ...
Lynch Tadhg +7 more
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The Toxic Effect Of Sildenafil Citrate On Adult Albino Rat Testis And The Possible Protective Role Of Royal Jelly (Histological And Immunohistochemical Study) [PDF]
The Egyptian Journal of Histology, 2019 Background: Phosphodiesterase inhibitor was appearing as a magic tool in treatment of erectile dysfunction, however, it might lead to harmful effects in high dose and long term administration.
Hanan Elkerdasy, Ali Mohamed
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