Results 31 to 40 of about 3,813 (172)

Ventricular tachycardia after administration of sildenafil citrate: a case report

Journal of Medical Case Reports, 2007
Background It has not previously been reported that sildenafil citrate causes malignant arrhythmias in humans. Case presentation A 41-year-old man developed sustained ventricular tachycardia following sildenafil citrate administration.
Rasmussen Jeppe G, Toft Egon, Frøbert Ole   +2 more
doaj   +1 more source

If We Cannot Use Nitric Oxide for Newborn Persistent Pulmonary Hypertension, is Oral Sildenafil Therapeutic? A Single-center Experience

Clinical and Experimental Obstetrics & Gynecology, 2022
Background: Persistent pulmonary hypertension is still an issue in newborn period with different treatment strategies. In this study, we aimed to evaluate the three-year experience of a neonatal intensive care unit on use of sildenafil citrate for ...
Selçuk Gürel
doaj   +1 more source

Sildenafil citrate (Viagra)

Intensive and Critical Care Nursing, 1999
Sildenafil is the first of a series of orally active treatments for MED which has resulted in unprecedented demand for treatment and potentially high cost to the NHS. Further oral therapies are likely to follow in the next year or so. In clinical trials, sildenafil produced an erection (sufficient to achieve intercourse) lasting up to 4 h on around 70%
openaire   +3 more sources

Effect of topically applied sildenafil citrate on wound healing: experimental study

Biomolecules & Biomedicine, 2014
Wound healing is a complex process that necessitates organization of different cell types and several signalling molecules. The aim of this study is to evaluate the effect of different concentrations of sildenafil citrate, which decreases cGMP ...
Koray Gürsoy, Melike Oruç, Yüksel Kankaya, Mustafa Gürhan Ulusoy, Uğur Koçer, Duygu Kankaya, Reyhan Neslihan Gürsoy, Özge Çevik, Elmas Öğüş, Vildan Fidanci   +9 more
doaj   +1 more source

Metabolic Markers as Potential Risk Factors in Pulmonary Hypertension

Pulmonary Circulation, Volume 16, Issue 3, July 2026.
ABSTRACT Pulmonary hypertension (PH) is a condition characterized by elevated mean pulmonary arterial pressure confirmed by right heart catheterization. PH involves both structural and functional changes in the pulmonary vascular bed. Since 2022, a four‐level risk stratification has been used to predict 1‐year mortality at follow‐up.
Sarah McGarrity, Pär I Johansson, Jørn Carlsen   +2 more
wiley   +1 more source

Development and Physicochemical Stability of an Oral GS‐441524 Suspension for Weight‐Adjusted Treatment of Feline Infectious Peritonitis

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
A 50 mg/mL oral GS‑441524 suspension for feline infectious peritonitis (FIP) was developed and shown to remain physico‐chemically stable for at least 12 weeks under tested storage conditions and 28 days in‑use, supporting accurate weight‑adjusted dosing as an extemporaneously compounded formulation under veterinary supervision.
Cédric Wernli, Ursula Streit
wiley   +1 more source

Pharmacokinetics, pharmacodynamics, and safety interaction study of tunodafil hydrochloride and alcohol: A randomized, blinded, placebo‐controlled, three‐cycle crossover study in Chinese healthy men

Andrology, Volume 14, Issue 2, Page 466-479, February 2026.
Abstract Objectives This study aimed to evaluate the pharmacodynamic effects of administering tunodafil hydrochloride with alcohol on blood pressure and heart rate in healthy Chinese males, and to investigate the mutual pharmacokinetic interactions and safety of the combination.
Dingyuan Hu, Suping Niu, Fan Huang, Lu Jin, Qun Gu, Yanting Li, Chongyou Lee, Zhenwei Xie, Xiangxing Liu, Fang Men, Wenyan Zhao, Shuang Li, Yian Liu, Qian Wang, Huaying Fan, Jiaojiao Zhang, Shuangshuang Lin, Liming Chen, Yi Fang   +18 more
wiley   +1 more source

Targeting G3BP1 Condensate Topology Promotes Stress Granule Assembly via m6A‐IGF2BP1 for Ischemic Stroke Rescue

Advanced Science, Volume 13, Issue 6, 30 January 2026.
Our research reveals that small‐molecule icariin (ICA) directly binds Ras‐GTPase‐activating protein SH3 domain‐binding protein 1 (G3BP1), inducing conformational change and oligomerization. This interaction confers neuroprotection by recruiting insulin‐like growth factor 2 mRNA‐binding protein 1 (IGF2BP1) and modulating N6‐methyladenosine (m6A ...
Ling Li, Yong‐Dong Guo, Xiao‐Wen Zhang, Zhi‐Yong Du, Yu‐Qi Wang, Zhuo Yang, Qian‐Wei Luo, Fang‐Fang Zhuo, Tian‐Tian Wei, Zheng‐Ping Liu, Bo Han, Wei Yu, Pei‐Pei Zhang, Wei Zhou, Zhi‐Yuan Lu, Peng‐Fei Tu, Chun‐Hong Zheng, Ke‐Wu Zeng   +17 more
wiley   +1 more source

Utilization of Fertility Treatment in Japan During the First Year of Insurance Coverage: Analysis of Real‐World Health Claims Data

Reproductive Medicine and Biology, Volume 25, Issue 1, January/December 2026.
ABSTRACT Purpose In April 2022, fertility treatments, including assisted reproductive technology (ART), became eligible for public health insurance coverage in Japan. This study describes the prevalence and characteristics of infertility diagnoses and fertility treatments during the first year of coverage.
Makoto Okawara, Tomoichiro Kuwazuru, Moe Masunaga, Kenji Fujimoto, Masako Nagata, Takeshi Iwasa, Yoshihisa Fujino   +6 more
wiley   +1 more source

Bioinspired Electrospun Chitosan–Based Materials for Tissue Regeneration

Advances in Polymer Technology, Volume 2026, Issue 1, 2026.
Chitosan (CS) is a cationic biopolymer that has shown unique opportunities in tissue engineering. The well‐defined geometry, porosity, easy processability, and antimicrobial and antifungal properties are particularly beneficial for tissue regeneration.
Teboho Clement Mokhena, Asanda Mtibe, Lerato Hlekelele, Amos Nhlapo, Katekani Shingange, Sivuyisiwe Mapukata, Antonio Benjamim Mapossa, Mokgaotsa Jonas Mochane, Eric Mathete, Ndivhuwo Shumbula, Odireleng Martin Ntwaeaborwa, Srijoni Sengupta   +11 more
wiley   +1 more source