Results 11 to 20 of about 3,518 (133)
Bioequivalence and Bioavailability of an Orodispersible Tablet of Sildenafil Citrate in Healthy Chinese Male Subjects. [PDF]
Clin Pharmacol Drug Dev, 2020 Lv Y +8 more
europepmc +2 more sources
Development of a Sildenafil Citrate Microemulsion-Loaded Hydrogel as a Potential System for Drug Delivery to the Penis and Its Cellular Metabolic Mechanism. [PDF]
Pharmaceutics, 2020 Atipairin A +5 more
europepmc +2 more sources
Clinical update on sildenafil citrate [PDF]
British Journal of Clinical Pharmacology, 2002 The timing of this edition's supplement containing papers on the pharmacokinetic and pharmacodynamic properties of sildenafil citrate (Viagra®, Pfizer) appears very apt. It comes at a time when sildenafil has been marketed in Europe for approximately 3 years and when there is increasing interest and focus on men's health. Indeed a recent edition of the
Ian H, Osterloh, Alan, Riley
openaire +2 more sources
Sildenafil citrate monohydrate [PDF]
Acta Crystallographica Section E Structure Reports Online, 2005 Sildenafil citrate is well known as Viagra for the treatment of erectile dysfuncion. In the title compound (systematic name: 1-{[3-(6,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl}-4-methylpiperazinium citrate monohydrate), C22H31N6O4S+·C6H7O7−·H2O, the pyrazolopyrimidone ring system and the ...
Yathirajan, H. S. +3 more
openaire +2 more sources
Effect of sildenafil citrate on the cardiovascular system [PDF]
Brazilian Journal of Medical and Biological Research, 2005 Sildenafil citrate is a drug commonly used to manage erectile dysfunction. It is designated chemically as 1-[[3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H -pyrazolo[4,3-d]pyrimidin-5-yl)-4 ethoxyphenyl] sulfonyl]-4-methylpiperazine citrate (C22H30N6(O4)S). It is a highly selective inhibitor of cyclic guanine monophosphate-specific phosphodiesterase type 5.
Shinlapawittayatorn, K. +2 more
openaire +5 more sources
Intensive and Critical Care Nursing, 1999 Sildenafil is the first of a series of orally active treatments for MED which has resulted in unprecedented demand for treatment and potentially high cost to the NHS. Further oral therapies are likely to follow in the next year or so. In clinical trials, sildenafil produced an erection (sufficient to achieve intercourse) lasting up to 4 h on around 70%
openaire +3 more sources
Advanced Science, Volume 13, Issue 6, 30 January 2026.Our research reveals that small‐molecule icariin (ICA) directly binds Ras‐GTPase‐activating protein SH3 domain‐binding protein 1 (G3BP1), inducing conformational change and oligomerization. This interaction confers neuroprotection by recruiting insulin‐like growth factor 2 mRNA‐binding protein 1 (IGF2BP1) and modulating N6‐methyladenosine (m6A ...
Ling Li +17 more
wiley +1 more source
Reproductive Medicine and Biology, Volume 25, Issue 1, January/December 2026.ABSTRACT Purpose In April 2022, fertility treatments, including assisted reproductive technology (ART), became eligible for public health insurance coverage in Japan. This study describes the prevalence and characteristics of infertility diagnoses and fertility treatments during the first year of coverage.
Makoto Okawara +6 more
wiley +1 more source
Bioinspired Electrospun Chitosan–Based Materials for Tissue Regeneration
Advances in Polymer Technology, Volume 2026, Issue 1, 2026.Chitosan (CS) is a cationic biopolymer that has shown unique opportunities in tissue engineering. The well‐defined geometry, porosity, easy processability, and antimicrobial and antifungal properties are particularly beneficial for tissue regeneration.
Teboho Clement Mokhena +11 more
wiley +1 more source
Andrologia, Volume 2026, Issue 1, 2026.Erectile dysfunction (ED) is a common sexual disorder worldwide significantly affects men’s quality of life. However, there remains a lack of comprehensive bibliometric analysis of ED treatment. This study aims to utilize bibliometric methods to assess the research progress in ED treatment and identify the research hot spots and emerging trends in this
Kefan Li +13 more
wiley +1 more source