Results 51 to 60 of about 3,813 (172)

The Concise Guide to PHARMACOLOGY 2025/26: Transporters

open access: yesBritish Journal of Pharmacology, Volume 182, Issue S1, Page S404-S496, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander   +28 more
wiley   +1 more source

INTESTINAL ABSORPTION AND PRESYSTEMIC DISPOSITION OF SILDENAFIL CITRATE IN THE RABBIT: EVIDENCE FOR SITEDEPENDENT ABSORPTIVE CLEARANCE [PDF]

open access: yesBulletin of Pharmaceutical Sciences. Assiut University, 2005
Sildenafil citrate is the first oral treatment of erectile dysfunction. Its oral bioavailability is about 40%. This research characterized the intestinal transport parameters of sildenafil citrate in rabbit using in situ intestinal perfusion technique ...
M. Hedaya, G. El Maghraby, M. Osman
doaj   +1 more source

“I'd rather die”: Patients' will and decision‐making practice in Japanese community psychiatry

open access: yesMedical Anthropology Quarterly, Volume 39, Issue 4, December 2025.
Abstract Recent mental health reforms have embraced patient autonomy and shared decision‐making, where care unfolds through collaboration between clinicians and patients. However, how decision‐making can improve in marginalized psychiatric clinics remains unclear.
Yuto Kano
wiley   +1 more source

Electroretinography and immunohistochemistry of retina in rabbits treated with sildenafil citrate

open access: yesArquivo Brasileiro de Medicina Veterinária e Zootecnia, 2015
Sildenafil citrate is a type-5 phosphodiesterase inhibitor (PDE-5), able to inhibit type-6 phosphodiesterase (PDE-6) as well, providing clinical benefits and paraeffects, some of them potentially related to the retina.
A.V.C. Amaral   +7 more
doaj   +1 more source

Real‐World Study on the Impact of Novel Coronavirus Infection on Male Erectile Function

open access: yesClinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT This study aims to examine the impact of novel coronavirus (COVID‐19) infection on male erectile function and to identify potential influencing factors. Male participants aged 18–65 years from Beijing and Shanghai were included in the study. A post‐COVID‐19 sexual function questionnaire was utilized for data collection.
Chuhong Chen   +6 more
wiley   +1 more source

Prognostic Value of Intrarenal Venous Flow Analysis Using Pulsed‐Wave Doppler Ultrasonography in Dogs with Myxomatous Mitral Valve Disease

open access: yesJournal of Veterinary Internal Medicine, Volume 39, Issue 6, November/December 2025.
ABSTRACT Background The predictive value of intrarenal Doppler ultrasonography (IRD) analysis using pulsed‐wave Doppler for survival in dogs with myxomatous mitral valve disease (MMVD) remains unknown. Hypothesis/Objectives Impaired IRD indices, such as a high venous impedance index (VII), are associated with a short survival time in dogs with MMVD ...
Tomoya Morita   +2 more
wiley   +1 more source

Impact of Tamoxifen on Endometrial Thickness in Women With Thin Endometrium Following Estrogen Therapy During Frozen–Thawed Embryo Transfer

open access: yesClinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT Endometrial thickness (ET) is an important parameter of determining endometrial receptivity for in vitro fertilization (IVF) with frozen–thawed embryo transfer (FET). ET is influenced by various intrinsic and extrinsic factors, such as hormonal fluctuations, age‐related changes, underlying medical conditions, and metabolic factors.
Masoumeh Zaree   +6 more
wiley   +1 more source

A Systematic Literature Review Exploring the Efficacy and Safety of Tadalafil and Sildenafil in Pulmonary Arterial Hypertension

open access: yesPulmonary Circulation, Volume 15, Issue 4, October 2025.
ABSTRACT Pulmonary Arterial Hypertension (PAH) is a rare, chronic and progressive disease affecting the heart and lungs. Endothelin receptor antagonist (ERA) + phosphodiesterase type 5 inhibitor (PDE5i) treatment is recommended for all PAH patients. The two approved PDE5is are tadalafil and sildenafil.
Rajan Saggar   +9 more
wiley   +1 more source

Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review

open access: yesChemistry &Biodiversity, Volume 22, Issue 9, September 2025.
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves   +3 more
wiley   +1 more source

Evaluation of the Efficacy and Safety of Topical Sildenafil Citrate Solution in the Treatment of Female Pattern Hair Loss [PDF]

open access: yesInternational Journal of Medical Arts
Introduction: Female pattern hair loss [FPHL] is a type of hair thinning that occurs in females, categorized by a steady drop in the number of hairs, specifically in the central, frontal & parietal regions of the scalp. It does not cause scarring. Female
Heba Mostafa   +2 more
doaj   +1 more source

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