Results 41 to 50 of about 3,731 (172)
ABSTRACT Background The predictive value of intrarenal Doppler ultrasonography (IRD) analysis using pulsed‐wave Doppler for survival in dogs with myxomatous mitral valve disease (MMVD) remains unknown. Hypothesis/Objectives Impaired IRD indices, such as a high venous impedance index (VII), are associated with a short survival time in dogs with MMVD ...
Tomoya Morita +2 more
wiley +1 more source
ABSTRACT Endometrial thickness (ET) is an important parameter of determining endometrial receptivity for in vitro fertilization (IVF) with frozen–thawed embryo transfer (FET). ET is influenced by various intrinsic and extrinsic factors, such as hormonal fluctuations, age‐related changes, underlying medical conditions, and metabolic factors.
Masoumeh Zaree +6 more
wiley +1 more source
Sildenafil citrate therapy for IUGR and its effect on umbilical artery Doppler
Background Intrauterine growth restriction (IUGR) occurs when there is deficiency of gas exchange and nutrient delivery to the fetus not allowing it to thrive in utero. This happens because of maternal diseases that decrease oxygen-carrying capacity (e.g.
Abdel A.G.E.-D.T El-Darwish +2 more
doaj +1 more source
ABSTRACT Pulmonary Arterial Hypertension (PAH) is a rare, chronic and progressive disease affecting the heart and lungs. Endothelin receptor antagonist (ERA) + phosphodiesterase type 5 inhibitor (PDE5i) treatment is recommended for all PAH patients. The two approved PDE5is are tadalafil and sildenafil.
Rajan Saggar +9 more
wiley +1 more source
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves +3 more
wiley +1 more source
Chondrodystrophic Dogs as a Preclinical Large Animal Model of Discogenic Back Pain
This study aims to validate an underutilized canine preclinical model of discogenic back pain model by deep phenotyping several structural and pain associated outcomes with novel findings in the areas of RNA sequencing and whole patch clamp of canine dorsal root ganglion neurons.
Mary K. Heimann +18 more
wiley +1 more source
Identifying Causal Inflammatory Factors With Gene Mediators and Potential Drugs for Bronchiectasis
Four inflammatory factors were identified with causal links to bronchiectasis: macrophage migration inhibitory factor (MMIF) showed a protective effect, whereas interleukin‐4 (IL‐4), interferon‐gamma (IFN‐γ), and basic fibroblast growth factor (FGF‐Basic) were associated with increased risk.
Wanzhe Liao +11 more
wiley +1 more source
This article elaborates on the role of NK cells in early pregnancy from multiple perspectives, including molecular mechanisms and therapeutic interventions. It also discusses how NK cell dysfunction contributes to RSA and RIF, aiming to provide insights for future research on NK cell mechanisms and clinical treatment of RSA and RIF.
Defeng Guan +5 more
wiley +1 more source
Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan +4 more
wiley +1 more source
EFFECT OF SILDENAFIL CITRATE ON THE BODY WEIGHT, BLOOD GLUCOSE AND WHITE BLOOD CELL COUNT DURING WOUND HEALING PROCESS IN DIABETIC RATS [PDF]
Background: Diabetes mellitus is a chronic metabolic disorder with major complication of delayed wound healing. Objectives: The purpose of this study was to evaluate the effect of sildenafil on blood glucose level, body weight and leucocyte count during ...
Ngulde SI +8 more
doaj

