Results 141 to 150 of about 206,958 (317)

“The Horror” of Silence: Gendered and Racial Absences in Joseph Conrad’s “Heart of Darkness” [PDF]

open access: yes
openThis thesis explores the racial and gendered silences in Joseph Conrad’s Heart of Darkness, examining how the novella reflects and reinforces the ideology of European imperialism. Drawing on historical context and postcolonial and feminist theory, it
POPOVA, VALERIIA
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

The art of dialogic silence in the way of tea

open access: yes, 2019
In this article I explore silence as dialogue in human communication and address its relevance to silence in heritage sites and museums. Instead of treating silent responses as negative or pedagogical failure, I approach silence from an eclectic ...
Murakami, K.
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Silence, Exile and Coming Second

open access: yes, 2016
Silence, exile and coming second: women writers get same raw deal as in theatre On Nollaig na mBan, when woman are traditionally given a break, Fiona O’Connor issues a wake-up call.
O'Connor, F.
core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

‘The Critical Agency of the ‘Avatar-I’: accessing the silence of the inaudible’

open access: yes, 2016
Can we access the plurality of our contemporary world through silence? And to what do the limits of our sonic imagination attest to? Artist and writer Salomé Voegelin re-listens to the body in silence, so as to grant a new agency, whereby she repositions
Voegelin, Salomé
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Review: Silence, Music, Silent Music,

open access: yes, 2008
A book review of Silence, Music, Silent Music, Edited by Nicky Losseff & Jenny ...
Bunt, Leslie
core  

The Roaring Ghosts: Depictions of female silence and its oppositions

open access: yes, 2021
Any examination of female silence and speech has to consider the context in which such images were created. An examination shows that despite two World Wars, social attitudes to female silence barely shifted from beliefs held during the Renaissance to ...
McCrory, Moy
core  

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