Results 101 to 110 of about 281,837 (328)
Neural Regeneration ResearchLoss of synapse and functional connectivity in brain circuits is associated with aging and neurodegeneration, however, few molecular mechanisms are known to intrinsically promote synaptogenesis or enhance synapse function.
Yuehua Cui +9 more
doaj +1 more source
Fast temporal adaptation of on-off units in the first optic chiasm of the blowfly [PDF]
, 1991 We recorded from spiking units in the first optic chiasm between lamina and medulla in the brain of the blowfly (Calliphora vicina). Both previously characterized neuron types, on-off units and sustaining units, were encountered.
Hateren, J.H. van,, Jansonius, N.M.,
core +2 more sources
Behavioural Brain Research, 2020 Silent infarcts (SI) are subcortical cerebral infarcts that occur in the absence of clinical symptoms commonly associated with ischemia and are linked to dementia development. Little is known about the pathophysiology underlying the cognitive dysfunction
C. Finney +3 more
semanticscholar +1 more source
Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein +13 more
wiley +1 more source
Metaplasticity at CA1 Synapses by Homeostatic Control of Presynaptic Release Dynamics
Cell Reports, 2017 Summary: Hebbian and homeostatic forms of plasticity operate on different timescales to regulate synaptic strength. The degree of mechanistic overlap between these processes and their mutual influence are still incompletely understood.
Cary Soares +2 more
doaj +1 more source
Neuronal Glutamatergic Network Electrically Wired with Silent But Activatable Gap Junctions
Journal of Neuroscience, 2020 It is widely assumed that electrical synapses in the mammalian brain, especially between interneurons, underlie neuronal synchrony. In the hippocampus, principal cells also establish electrical synapses with each other and have also been implicated in ...
Diana J Ixmatlahua +6 more
semanticscholar +1 more source
Neuropsychiatric Symptoms Mimicking Dementia in a Patient Treated With Imatinib
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Tyrosine kinase inhibitors are the cornerstone of chronic myeloid leukemia treatment. Newer agents have more potency and a broader spectrum of action, but also a higher potential for neuropsychiatric side effects. We present a case of a patient on imatinib who developed progressive cognitive, mood, and behavioral alterations.
Ashley Jones +3 more
wiley +1 more source
Dynamin-dependent NMDAR endocytosis during LTD and its dependence on synaptic state
BMC Neuroscience, 2005 Background The N-methyl-D-aspartate (NMDA)-type glutamate receptor expressed at excitatory glutamatergic synapses is required for learning and memory and is critical for normal brain function.
Hanson Jesse E +3 more
doaj +1 more source
Advanced Functional Materials, EarlyView.This study demonstrated single‐crystalline PbTiO3‐based memristors with atomically sharp interfaces, well‐ordered lattices, and minimal lattice mismatch. The devices exhibited an ON/OFF ratio exceeding 105, high stability, and rich resistance‐state modulation.
Haining Li +7 more
wiley +1 more source
Roles of Voltage-Dependent Sodium Channels in Neuronal Development, Pain, and Neurodegeneration
Journal of Pharmacological Sciences, 2006 Besides initiating and propagating action potentials in established neuronal circuits, voltage-dependent sodium channels sculpt and bolster the functional neuronal network from early in embryonic development through adulthood (e.g., differentiation of ...
Akihiko Wada
doaj +1 more source