Results 51 to 60 of about 281,837 (328)
Stochastic Synapses Enable Efficient Brain-Inspired Learning Machines [PDF]
, 2016 Recent studies have shown that synaptic unreliability is a robust and sufficient mechanism for inducing the stochasticity observed in cortex. Here, we introduce Synaptic Sampling Machines, a class of neural network models that uses synaptic stochasticity
Al-Shedivat, Maruan +4 more
core +2 more sources
Proceedings of the National Academy of Sciences of the United States of America, 2021 Significance During critical periods, restricted time windows in early brain development, cortical neural circuits get refined in an experience-dependent manner.
Rashad Yusifov +4 more
semanticscholar +1 more source
In Vivo Cocaine Experience Generates Silent Synapses [PDF]
Neuron, 2009 Studies over the past decade have enunciated silent synapses as prominent cellular substrates for synaptic plasticity in the developing brain. However, little is known about whether silent synapses can be generated postdevelopmentally. Here, we demonstrate that highly salient in vivo experience, such as exposure to cocaine, generates silent synapses in
Huang, Yanhua H +12 more
openaire +4 more sources
Self-repair in a Bidirectionally Coupled Astrocyte-Neuron (AN) System based on Retrograde Signaling
Frontiers in Computational Neuroscience, 2012 In this paper we demonstrate that retrograde signaling via astrocytes may underpin self-repair in the brain. Faults manifest themselves in silent or near silent neurons caused by low transmission probability synapses; the enhancement of the transmission ...
John eWade +4 more
doaj +1 more source
ARHGAP12 Functions as a Developmental Brake on Excitatory Synapse Function
Cell Reports, 2016 The molecular mechanisms that promote excitatory synapse development have been extensively studied. However, the molecular events preventing precocious excitatory synapse development so that synapses form at the correct time and place are less well ...
W. Ba +13 more
doaj +1 more source
The role of inhibitory feedback for information processing in thalamocortical circuits [PDF]
, 2006 The information transfer in the thalamus is blocked dynamically during sleep, in conjunction with the occurence of spindle waves. As the theoretical understanding of the mechanism remains incomplete, we analyze two modeling approaches for a recent ...
A. Destexhe +23 more
core +2 more sources
Cell Reports, 2017 GABAergic activity is important in neocortical development and plasticity. Because the maturation of GABAergic interneurons is regulated by neural activity, the source of excitatory inputs to GABAergic interneurons plays a key role in development.
Rongkang Deng +2 more
doaj +1 more source
Potential mechanisms for imperfect synchronization in parkinsonian basal ganglia [PDF]
, 2012 Neural activity in the brain of parkinsonian patients is characterized by the intermittently synchronized oscillatory dynamics. This imperfect synchronization, observed in the beta frequency band, is believed to be related to the hypokinetic motor ...
Park, Choongseok, Rubchinsky, Leonid
core +3 more sources
Silent Synapses in Neural Plasticity: Current Evidence [PDF]
Learning & Memory, 1999 Silent synapses, defined as structural specializations for neurotransmission that do not produce a physiological response in the receiving cell, may occur frequently in neural circuits. Their recruitment to physiological effectiveness may be an important component of circuit modification.
H L, Atwood, J M, Wojtowicz
openaire +2 more sources
Frontiers in Neuroanatomy, 2019 The thalamocortical circuit is of central importance in relaying information to the cortex. In development, subplate neurons (SPNs) form an integral part of the thalamocortical pathway.
Patrick O. Kanold +2 more
doaj +1 more source