Results 61 to 70 of about 24,094 (177)
Silent Synapses Sit and Wait for a Better Day [PDF]
Neuron, 2009 Synaptic activity is thought to be critical for synaptic stabilization. In this issue of Neuron, Krishnaswamy and Cooper show that nicotinic synapses on autonomic neurons remain intact without synaptic activity. Postsynaptic responses are required, however, for presynaptic terminals to acquire the high-affinity choline transporter necessary for high ...
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Silent synapses dictate cocaine memory destabilization and reconsolidation [PDF]
Nature Neuroscience, 2019 Cocaine-associated memories are persistent, but, on retrieval, become temporarily destabilized and vulnerable to disruptions, followed by reconsolidation. To explore the synaptic underpinnings for these memory dynamics, we studied AMPA receptor (AMPAR)-silent excitatory synapses, which are generated in the nucleus accumbens by cocaine self ...
William J. Wright +13 more
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Developmental synaptic changes at the transient olivocochlear-inner hair cell synapse [PDF]
, 2019 In the mature mammalian cochlea, inner hair cells (IHCs) are mainly innervated by afferent fibers that convey sound information to the CNS. During postnatal development, however, medial olivocochlear (MOC) efferent fibers transiently innervate the IHCs ...
Elgoyhen, Ana Belen +5 more
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Evidence for silent synapses: Implications for the expression of LTP
Neuron, 1995 Recent work has suggested that some proportion of excitatory synapses on hippocampal CA1 pyramidal cells that express NMDA receptors (NMDARs) may not express functional AMPA receptors (AMPARs), thus making these synapses silent at the resting membrane potential.
Robert C. Malenka +2 more
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Speaking Out of Turn: A Role for Silent Synapses in Pain [PDF]
IUBMB Life, 1999 AbstractSevere tissue or nerve injury can result in a chronic and inappropriate sensation of pain, mediated in part by the sensitization of spinal dorsal horn neurons to input from primary afferent fibers. Synaptic transmission at primary afferent synapses is mainly glutamatergic.
Min Zhuo, Ping Li, Geoffrey A. Kerchner
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An Online Structural Plasticity Rule for Generating Better Reservoirs
, 2016 In this article, a novel neuro-inspired low-resolution online unsupervised learning rule is proposed to train the reservoir or liquid of Liquid State Machine. The liquid is a sparsely interconnected huge recurrent network of spiking neurons. The proposed
Basu, Arindam, Roy, Subhrajit
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Recent updates on incubation of drug craving: a mini-review [PDF]
, 2015 Cue-induced drug craving progressively increases after prolonged withdrawal from drug self-administration in laboratory animals, a behavioral phenomenon termed 'incubation of drug craving.' Studies over the years have revealed several important neural ...
Abdolahi +39 more
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Cell Reports, 2018 Heightened neural excitability in infancy and childhood results in increased susceptibility to seizures. Such early-life seizures are associated with language deficits and autism that can result from aberrant development of the auditory cortex.
Hongyu Sun +5 more
doaj +1 more source
Geometric Analysis of Synchronization in Neuronal Networks with Global Inhibition and Coupling Delays [PDF]
, 2017 We study synaptically coupled neuronal networks to identify the role of coupling delays in network's synchronized behaviors. We consider a network of excitable, relaxation oscillator neurons where two distinct populations, one excitatory and one ...
Campbell, Sue Ann, Ryu, Hwayeon
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Short-Term Memory Through Persistent Activity: Evolution of Self-Stopping and Self-Sustaining Activity in Spiking Neural Networks [PDF]
, 2014 Memories in the brain are separated in two categories: short-term and long-term memories. Long-term memories remain for a lifetime, while short-term ones exist from a few milliseconds to a few minutes.
Hubert, Julien, Ikegami, Takashi
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