Results 81 to 90 of about 24,094 (177)

Building a realistic, scalable memory model with independent engrams using a homeostatic mechanism

open access: yesFrontiers in Neuroinformatics
Memory formation is usually associated with Hebbian learning and synaptic plasticity, which changes the synaptic strengths but omits structural changes.
Marvin Kaster   +4 more
doaj   +1 more source

The effect of heterogeneity on decorrelation mechanisms in spiking neural networks: a neuromorphic-hardware study [PDF]

open access: yes, 2014
High-level brain function such as memory, classification or reasoning can be realized by means of recurrent networks of simplified model neurons. Analog neuromorphic hardware constitutes a fast and energy efficient substrate for the implementation of ...
Diesmann, Markus   +6 more
core   +5 more sources

Dynamin-dependent NMDAR endocytosis during LTD and its dependence on synaptic state

open access: yesBMC Neuroscience, 2005
Background The N-methyl-D-aspartate (NMDA)-type glutamate receptor expressed at excitatory glutamatergic synapses is required for learning and memory and is critical for normal brain function.
Hanson Jesse E   +3 more
doaj   +1 more source

SynGAP isoforms exert opposing effects on synaptic strength [PDF]

open access: yes, 2012
Peer reviewedPublisher ...
,   +13 more
core   +3 more sources

Double Inverse Stochastic Resonance with Dynamic Synapses

open access: yes, 2016
We investigate the behavior of a model neuron that receives a biophysically-realistic noisy post-synaptic current based on uncorrelated spiking activity from a large number of afferents.
Barreto, E.   +4 more
core   +1 more source

The Effect of Different Forms of Synaptic Plasticity on Pattern Recognition in the Cerebellar Cortex [PDF]

open access: yes, 2009
“The original publication is available at www.springerlink.com”. Copyright Springer.Many cerebellar learning theories assume that long-term depression (LTD) of synapses between parallel fibres (PFs) and Purkinje cells (PCs) provides the basis for pattern
Adams, R.G.   +4 more
core   +1 more source

At immature mossy fibers-CA3 connections, activation of presynaptic GABAB receptors by endogenously released GABA contributes to synapses silencing

open access: yesFrontiers in Cellular Neuroscience, 2009
Early in postnatal life correlated GABAergic activity in the hippocampus is thought to play a crucial role in synaptogenesis and in the development of adult neuronal networks. Unlike adulthood, at this developmental stage, mossy fibers (MF) which are the
Victoria F Safiulina, Enrico Cherubini
doaj   +1 more source

Electrophysiological Organization of the Eye of Aplysia [PDF]

open access: yes, 1969
The eye of Aplysia californica was studied by electrophysiological and histological methods. It has a central spheroidal lens which is surrounded by a retina composed of several thousand receptor cells which are replete with clear vesicles, pigmented ...
Jacklet, Jon W.
core   +1 more source

Silent synapses in pain-related anterior cingulate cortex

open access: yesMolecular Pain, 2023
Synaptic plasticity such as Long-term potentiation (LTP) is a key mechanism for learning in central synapses including the cortex. There are two least two major forms of LTPs: presynaptic LTP and postsynaptic LTP. For postsynaptic LTP, the potentiation of AMPA receptor-mediated responses through protein phosphorylation is thought to be a key mechanism.
openaire   +2 more sources

Progressive maturation of silent synapses governs the duration of a critical period [PDF]

open access: yesProceedings of the National Academy of Sciences, 2015
Significance During critical periods, cortical neural circuits are refined to optimize their functional properties. The prevailing notion is that the balance between excitation and inhibition determines the onset and closure of critical periods.
Huang, Xiaojie   +9 more
openaire   +4 more sources

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