Results 91 to 100 of about 10,310 (224)
The Effect of Water Extracted Silibinin on Reactive Oxygen Species (ROS) Production of Macrophages [PDF]
, 2008 The world is actively looking for technology to produce sustainable liquid fuels to replace our reliance on petroleum-based fuels. Biomass can be converted either through the thermochemical or saccharification platforms into fuels such as ethanol or ...
Abbott, Julie +3 more
core +1 more source
Hepatitis C: From inflammatory pathogenesis to anti-inflammatory/hepatoprotective therapy [PDF]
, 2018 Hepatitis C virus (HCV) infection commonly causes progressive liver diseases that deteriorate from chronic inflammation to fibrosis, cirrhosis and even to hepatocellular carcinoma.
Huang, Meng-Hao +3 more
core +2 more sources
BioMed Research International, Volume 2026, Issue 1, 2026.The potential roles of chemical, physical, and viral factors in cancer development are well documented. Similarly, bacterial carcinogenesis has been reported previously, though not extensively. Therefore, we aimed to provide comprehensive, mechanistic evidence on the pathogenesis of bacteria‐induced carcinogenesis and possible treatments to halt cancer
Md Sohel +14 more
wiley +1 more source
Milk thistle (Silybum marianum) [PDF]
, 2006 Milk thistle is a commonly used herb for hepatic function and disorders.
Staff, Clinic
core +1 more source
Silodosin inhibits noradrenaline-activated transcription factors Elk1 and SRF in human prostate smooth muscle. [PDF]
, 2012 The transcription factors Elk1 and serum response factor (SRF) are central regulators of cell cycle and phenotype in various cell types. Elk1 is activated by phosphorylation (serine-383), while activation of SRF requires its co-factor, myocardin ...
Andersson, Karl-Erik +10 more
core +2 more sources
Biological Activity of Liposomal Silibinin
Антибиотики и Химиотерапия, 2020 The aim of the study was to obtain and characterize liposomal silibinin, as well as to study its antitumor and antimicrobial activity. Liposomes were obtained by hydration of a thin-layer film with a buffer solution followed by multiple freezing-thawing of the dispersion of phosphatidylcholine-cholesterol-silibinin.
N. B. Feldman +6 more
openaire +1 more source
Journal of Chemistry, Volume 2026, Issue 1, 2026.Breast cancer is the most common cancer among women. Triple‐negative breast cancer (TNBC) lacks hormone receptors and human epidermal growth factor receptor 2 expression and has aggressive behavior and poor prognosis; therefore, it has significant limitations and challenges in its treatment.
Nooshin Goudarzi +7 more
wiley +1 more source
Silibinin efficacy in a rat model of pulmonary arterial hypertension using monocrotaline and chronic hypoxia [PDF]
, 2019 Background C-X-C chemokine receptor type 4 (CXCR4) may be involved in the development of pulmonary arterial hypertension (PAH). CXCR4 inhibitor AMD3100 was described to have a positive effect on the prevention of pulmonary arterial muscularization in PAH
FURUTANI Yoshiyuki +7 more
core +2 more sources
An Overview on the Effects of Silibinin on Different MicroRNAs Expression in Cancer
Journal of Mazandaran University of Medical Sciences, 2018 MicroRNAs (miRNAs) are small non-coding RNAs that regulate the expression of about 60% of human genomes. Silibinin or mixture of silybin A and B is a flavonolignans that constitute 70-80% Silymarin which is considered to be its main effective ingredient.
Vahid Akbari Kordkheyli +4 more
doaj
Nrf2 Activation in Inflammatory Diseases: A Review of Natural and Synthetic Modulators
Oxidative Medicine and Cellular Longevity, Volume 2026, Issue 1, 2026.The nuclear factor erythroid 2–related factor 2 (Nrf2) pathway is a central regulator of the cellular antioxidant response, playing a key role in modulating inflammation and defending against oxidative stress‐induced damage. A range of natural and synthetic compounds, including dimethyl fumarate, bardoxolone, oltipraz, RTA‐408, ursodiol, curcumin ...
Vitória B. Costa +6 more
wiley +1 more source