Results 81 to 90 of about 10,310 (224)
Natural Products in Cancer Prevention and Therapy: Current Challenges and Future Directions
MedComm, Volume 7, Issue 2, February 2026.Natural products play a pivotal role in cancer therapy. They induce cancer cell death by reprogramming four metabolic pathways while precisely targeting the tumor microenvironment and immune cells. These compounds not only leverage novel delivery systems for innovative applications but also demonstrate unique therapeutic efficacy across clinical stages:
Ruimiao Qian +8 more
wiley +1 more source
Food Frontiers, Volume 7, Issue 1, January 2026.Schematic overview illustrating the anticancer mechanisms of selected natural products (resveratrol, quercetin, berberine) targeting EGFR and HER2 signaling pathways in tumor cells. These compounds inhibit receptor activation and downstream oncogenic cascades, including PI3K/Akt/mTOR, MAPK/ERK, and STAT3 pathways.
Iman Ramli +8 more
wiley +1 more source
Isolation of Active Substances from the Seeds of the Milk Thistle Plant (Silybum marianum) and Determination of Antioxidant Activity [PDF]
, 2011 Opisana je izolacija silimarina, smjese dobro definiranih flavonolignana, iz sjemena biljke sikavice (Silybum marianum). Silimarin je ekstrahiran acetonom iz deoleinizirana sjemena bez zagrijavanja. Iskorištenje je iznosilo Y = 4,1 %.
D. Gašo-Sokač, S. Kovač, V. Bušić
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Anti-cancer natural products isolated from chinese medicinal herbs [PDF]
, 2011 In recent years, a number of natural products isolated from Chinese herbs have been found to inhibit proliferation, induce apoptosis, suppress angiogenesis, retard metastasis and enhance chemotherapy, exhibiting anti-cancer potential both in vitro and in
Wen Tan +12 more
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Artificial Cells, Nanomedicine, and Biotechnology, 2019 Purpose This study aimed to assess the protective effects of silibinin on blue light-emitting diode (LED)-induced retinal ganglion cells (RGCs) damage.Methods Silibinin was applied in RGCs damage in vitro model to test its protective effects.
Ying Shen +6 more
doaj +1 more source
Silibinin: an old drug for hematological disorders
Oncotarget, 2017 Silibinin (silybin), a non-toxic natural polyphenolic flavonoid, is the principal and the most biologically active component of silymarin. It is efficient in the treatment of acute and chronic liver disorders caused by toxins, drug, alcohol, hepatitis, and gall bladder disorders. Further, in our previous studies, we explored the anti-cancer efficacy in
Zou, Hai +5 more
openaire +3 more sources
Exploring Autophagy Inducing Molecules: Targeting Diverse Pathways in Alzheimer's Disease Management
Medicinal Research Reviews, Volume 46, Issue 1, Page 272-298, January 2026.ABSTRACT Neurodegenerative disorders, including Alzheimer's disease (AD), impose a significant burden on society due to their progressive nature and the associated healthcare costs. Autophagy, a vital cellular degradation process, has emerged as a promising therapeutic target in these disorders.
Baljinder Singh +4 more
wiley +1 more source
The effect of silymarin on liver injury induced by Thioacetamide in rats [PDF]
, 2013 Introduction: In this study the protective effects of Silymarin was investigated against thioacetamide (TAA) induced hepatotoxicity in rat. Methods: In an experimental study 24 male Wistar rats were designated in four equal groups as follows: Control ...
Ahangar Darabi, Mahboobeh. +3 more
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Artichoke and milk thistle pills and syrups as sources of phenolic compounds with antimicrobial activity [PDF]
, 2016 Dietary supplements based on hepatoprotective plants have been increasingly used in the prevention of liver injuries. In the present work, the aim was to study the phenolic profile and possibly relate it to the in vitro antimicrobial activity of two ...
Alves, Maria José +4 more
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Phytotherapy Research, Volume 40, Issue 1, Page 77-99, January 2026.ABSTRACT Flavonoids are natural secondary metabolites of plants with a basic composition derived from polyphenols that can produce a plethora of different neurophysiological effects, some of which are relevant to anxiety disorders. As such, many flavonoids have been evaluated in behavioral screens in preclinical research on anxiolytics.
Jhennify Albuquerque Machado +7 more
wiley +1 more source