Results 11 to 20 of about 10,310 (224)

Silymarin Reduces the Inflammatory Response and the Burden of <i>Mycobacterium tuberculosis</i> H37Ra Infection in Human Lung A549 Cells. [PDF]

Int J Microbiol
Silymarin is a natural polyphenol known for its broad range of biological effects, and research conducted in macrophages and mice infected with Mycobacterium tuberculosis have highlighted its potential as a complementary treatment for tuberculosis. Silymarin modulates multiple cellular signaling pathways associated with various aspects of the immune ...
Hernández-Magaña NL, Hernandez De La Cruz ON, Castañón-Arreola M.   +2 more
europepmc   +2 more sources

Cosmeceuticals and silibinin [PDF]

Clinics in Dermatology, 2009
Cosmeceuticals are used for nourishing and improving the appearance of the skin and are also documented as effective agents for treating various dermatologic conditions. Cosmeceutical preparations from herbal origin are most popular among consumers because these agents are mostly nontoxic and possess strong antioxidant activity.
Rana P, Singh, Rajesh, Agarwal
openaire   +2 more sources

THE CHARACTERIZATION OF SILYMARIN AND SILIBININ LIPOSOMES [PDF]

Journal of Engineering & Processing Management, 2022
&lt;p&gt;The aim of the present study was the characterization of silymarin and silibinin liposomes via determination of encapsulation efficiency, particle size, polydispersity index (PDI), zeta potential, mobility, and conductivity, as well as storage stability during 28 days at 4&amp;ordm;C and stability after UV ...
Jovanović, Aleksandra, Dinić, Svetlana, Uskoković, Aleksandra, Arambašić Jovanović, Jelena, Grdović, Nevena, Vidaković, Melita, Mihailović, Mirjana   +6 more
openaire   +3 more sources

Silibinin Efficacy against Human Hepatocellular Carcinoma [PDF]

Clinical Cancer Research, 2005
Abstract Purpose: Hepatocellular carcinoma (HCC) is one of the most common recurrent malignancies, for which, currently, there is no effective therapy. Considering the antihepatotoxic activity of silibinin, a widely used drug and supplement for various liver disorders, together with its strong preventive and anticancer efficacy against ...
Leyon, Varghese, Chapla, Agarwal, Alpana, Tyagi, Rana P, Singh, Rajesh, Agarwal   +4 more
openaire   +2 more sources

Effect of Silibinin in Lowering the Intraocular Pressure in Normotensive Rabbits: Interaction with Pilocarpine and Cyclopentolate

Iraqi Journal of Pharmaceutical Sciences, 2017
Previous data indicated the effectiveness of silibinin as intraocular pressure (IOP) - lowering agent.  The present study was performed to evaluate the interaction of silibinin with pilocarpine or cyclopentolate in lowering IOP in normotensive rabbits ...
Saad A. Hussain, Haider M. Mohammed, Munaf H. Abdulrazzaq, Ahmed T. Numan   +3 more
doaj   +3 more sources

Effects of Polyphenols on Oxidative Stress-Mediated Injury in Cardiomyocytes [PDF]

, 2017
Cardiovascular diseases are the main cause of mortality and morbidity in the world. Hypertension, ischemia/reperfusion, diabetes and anti-cancer drugs contribute to heart failure through oxidative and nitrosative stresses which cause cardiomyocytes ...
Bei, Roberto, Benvenuto, Monica, Bergante, Sonia, Giganti, Maria Gabriella, Manzari, Vittorio, Masuelli, Laura, Mattera, Rosanna, Modesti, Andrea, Pluchinotta, Francesca Romana, Tettamanti, Guido, Tresoldi, Ilaria   +10 more
core   +5 more sources

Silibinin ameliorates deoxycholic acid-induced pyroptosis in steatotic HepG2 cells by inhibiting NLRP3 inflammasome activation

Biochemistry and Biophysics Reports, 2023
Nonalcoholic steatohepatitis (NASH) represents an inflammatory subtype of nonalcoholic fatty liver disease (NAFLD). The activation of the NOD-like receptor protein 3 (NLRP3) inflammasome triggers pyroptosis, thus propelling the progression from simple ...
Meiqing Mai, Ya Wang, Mengliu Luo, Zhongxia Li, Di Wang, Yongdui Ruan, Honghui Guo   +6 more
doaj   +1 more source

Multiple effects of silymarin on the hepatitis C virus lifecycle [PDF]

, 2010
Silymarin, an extract from milk thistle (Silybum marianum), and its purified flavonolignans have been recently shown to inhibit hepatitis C virus (HCV) infection, both in vitro and in vivo.
Bourne, Nigel, Brimacombe, Claire L, Cao, Feng, Graf, Tyler N, Grove, Joe, Kane, Olivia J, Lohmann, Volker, Martinez, Laura E, McKeating, Jane A, Nahmias, Yaakov, Negash, Amina, Oberlies, Nicholas H, Owen, David M, Polyak, Stephen J, Pécheur, Eve-Isabelle, Tavis, John E, Wagoner, Jessica   +16 more
core   +1 more source

Natural Compounds as Beneficial Antioxidant Agents in Neurodegenerative Disorders: A Focus on Alzheimer’s Disease [PDF]

, 2019
The positive role of nutrition in chronic neurodegenerative diseases (NDs) suggests that dietary interventions represent helpful tools for preventing NDs.
Antonella Amato, Flavia Mulè, Simona Terzo   +2 more
core   +1 more source

Silibinin and non-melanoma skin cancers

Journal of Traditional and Complementary Medicine, 2020
Skin is the largest human organ that shields the inner body from contact with xenobiotic and genotoxic agents, and in this process, the skin's cellular genome faces continuous stress due to direct exposure to these noxious factors. Accumulation of genetic stress results in genomic alterations leading to undesirable gene or protein alteration/expression
Ram Raj Prasad, Sandeep Paudel, Komal Raina, Rajesh Agarwal   +3 more
openaire   +3 more sources