Silico-Tuberculosis Mimicking Malignancy [PDF]
CureusSilico-tuberculosis is the combination of silicosis and tuberculosis (TB). Symptoms of TB such as dyspnea, cough, and hemoptysis may precede the diagnosis of an endo-bronchial mass lesion on chest imaging. Among workers who were exposed to silica, TB was more common, and experiments indicated that silica inhibits alveolar macrophage activity and severe
Elango, Ragavi +3 more
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A Complex Case of Pulmonary Silico-Tuberculosis and Review of Literature [PDF]
Diagnostics, 2023 Silicosis caused by the inhalation/deposition of free silica particles is characterized by pulmonary inflammation/fibrosis. Among the clinical disorders associated with silicosis, tuberculosis is by far the most prominent. A 66-year-old male non-smoker, originally from North Africa, reported a dry cough and significant weight loss.
D’Sa L. +7 more
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Prevalence of silicosis, tuberculosis among silicotic individuals, and silico-tuberculosis in India: A systematic review [PDF]
Lung IndiaSilicosis, a progressive and irreversible pneumoconiosis resulting from crystalline silica particle inhalation, represents a significant occupational health burden in India.
M. Deepaselvi +6 more
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1,2,3-Triazolyl indole-piperazine hybrids as potential anti-tubercular agents: design, synthesis, in vitro, and in silico evaluation [PDF]
RSC AdvancesTuberculosis remains one of the major infectious diseases and continues to pose a significant public health challenge globally. In the present study, two sets of novel 1,2,3-triazolyl indole-piperazine derivatives (R1–R17) were designed, synthesized and ...
Rajkumar Reddyrajula +7 more
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Silico-tuberculosis and associated risk factors in central province of Iran [PDF]
The Pan African Medical Journal, 2015 INTRODUCTION: co-existence of silicosis and tuberculosis is known as silico-tuberculosis. This article review the frequency of silicosis and tuberculosis in workers who exposed to silica and evaluate influencing factors that may increase the risk of ...
Aliasghar Farazi, Mansooreh Jabbariasl
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Systems-based approaches to probing metabolic variation within the Mycobacterium tuberculosis complex. [PDF]
PLoS ONE, 2013 The Mycobacterium tuberculosis complex includes bovine and human strains of the tuberculosis bacillus, including Mycobacterium tuberculosis, Mycobacterium bovis and the Mycobacterium bovis BCG vaccine strain. M. bovis has evolved from a M.
Emma K Lofthouse +7 more
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Bayesian Augmented Clinical Trials in TB Therapeutic Vaccination
Frontiers in Medical Technology, 2021 We propose a Bayesian hierarchical method for combining in silico and in vivo data onto an augmented clinical trial with binary end points. The joint posterior distribution from the in silico experiment is treated as a prior, weighted by a measure of ...
Dimitrios Kiagias +4 more
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A Nano-MgO and Ionic Liquid-Catalyzed 'Green' Synthesis Protocol for the Development of Adamantyl-Imidazolo-Thiadiazoles as Anti-Tuberculosis Agents Targeting Sterol 14α-Demethylase (CYP51). [PDF]
PLoS ONE, 2015 In this work, we describe the 'green' synthesis of novel 6-(adamantan-1-yl)-2-substituted-imidazo[2,1-b][1,3,4]thiadiazoles (AITs) by ring formation reactions using 1-(adamantan-1-yl)-2-bromoethanone and 5-alkyl/aryl-2-amino1,3,4-thiadiazoles on a nano ...
Sebastian Anusha +13 more
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A research study on morbidity including silicotuberculosis among the mine workers of Rajasthan
Journal of Integrated Health Sciences, 2013 Background: Stone mines of Western Rajasthan are famous worldwide for its sandstone and white marble. In the drought-stricken state of Rajasthan (in particular in its Western part) mining provides essential support to livelihood generation to more than 2
Prakash Tyagi, Rajesh Mehta
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Tuberculosis diagnosis using immunodominant, secreted antigens of Mycobacterium tuberculosis [PDF]
, 2013 Summary Tuberculosis (TB) remains a major public health concern in most low-income countries. Hence, rapid and sensitive TB diagnostics play an important role in detecting and preventing the disease. In addition to established diagnostic methods, several
Aliya, Bekmurzayeva +3 more
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