Results 1 to 10 of about 39,676 (261)
Integrated multi-omics analyses reveal the pro-inflammatory and pro-fibrotic pulmonary macrophage subcluster in silicosis [PDF]
Ecotoxicology and Environmental SafetyBackground: Silicosis is a lethal occupational disease caused by long-term exposure to respirable silica dust. Pulmonary macrophages play a crucial role in mediating the initiation of silicosis.
Hanyujie Kang +4 more
doaj +2 more sources
Signal Transduction and Targeted Therapy, 2022 Silicosis is the most prevalent and fatal occupational disease with no effective therapeutics, and currently used drugs cannot reverse the disease progress.
Ming-yao Wang, Junling Pang, Hao Yang
exaly +2 more sources
The Mechanism and Effect of Autophagy, Apoptosis, and Pyroptosis on the Progression of Silicosis [PDF]
International Journal of Molecular Sciences, 2021 Shi Chen
exaly +2 more sources
Health and safety in 3D printing
International Journal of Occupational and Environment Safety, 2022 Fused deposition modelling, or 3D printing, is an additive manufacturing technique that is quickly gaining popularity because of its ability to produce usable parts with several geometries. It provides multiple advantages in everyday life.
Héctor García, Teresa López Pola
doaj +1 more source
Particulate Matter Characterization in a Hospital’s Underground Car Park
Powders, 2022 The air quality in a hospital’s underground car park is a concern because diesel fumes from cars impact upon vulnerable people attending medical consultations. This research aims to quantify the potential health risk associated with a particular hospital
Hector Garcia-Gonzalez +4 more
doaj +1 more source
Blocking Caspase-1/Gsdmd and Caspase-3/-8/Gsdme pyroptotic pathways rescues silicosis in mice
PLoS Genetics, 2022 Millions of patients suffer from silicosis, but it remains an uncurable disease due to its unclear pathogenic mechanisms. Though the Nlrp3 inflammasome is involved in silicosis pathogenesis, inhibition of its classic downstream factors, Caspase-1 and ...
Lulu Kang +12 more
doaj +2 more sources
Frontiers in Genetics, 2021 Silicosis is a fatal occupational lung disease which currently has no effective clinical cure. Recent studies examining the underlying mechanism of silicosis have primarily examined experimental models, which may not perfectly reflect the nature of human
Junling Pang +13 more
doaj +1 more source
Anales del Sistema Sanitario de Navarra, 2005 Silicosis, which acquired great significance during the period of increase in mining and construction, continues to be a pathology with a high morbidity and mortality within pneumoconiosis. Exposure to silica produces pathological, clinical and radiological alterations that together with compatible personal antecedents suggests its diagnosis in a ...
Abú- Shams, K. +2 more
openaire +5 more sources
BMC Immunology, 2022 Background Tuberculosis infection is a major complication of silicosis, but there is no study on whether silicosis can affect the sensitivity of QuantiFERON-TB Gold In-Tube (QFT-GIT) assays.
Xin Yu +8 more
doaj +1 more source
Workplace Health & Safety, 2020 Occupational exposures to dust with elevated levels of respirable crystalline silica in artificial stone increase workers’ risk for silicosis.
Kimberly Reynolds, John Jerome
openaire +3 more sources